Antigenotoxic Effect of Trametes spp. Extracts against DNA Damage on Human Peripheral White Blood Cells
المؤلفون المشاركون
Živković, Lada
Spremo-Potparević, Biljana
Milovanović, Ivan
Stajić, Mirjana
Vukojević, Jelena
Knežević, Aleksandar
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Trametes species have been used for thousands of years in traditional and conventional medicine for the treatment of various types of diseases.
The goal was to evaluate possible antigenotoxic effects of mycelium and basidiocarp extracts of selected Trametes species and to assess dependence on their antioxidant potential.
Trametes versicolor, T.
hirsuta, and T.
gibbosa were the species studied.
Antigenotoxic potentials of extracts were assessed on human peripheral white blood cells with basidiocarp and mycelium extracts of the species.
The alkaline comet test was used for detection of DNA strand breaks and alkali-labile sites, as well as the extent of DNA migration.
DPPH assay was used to estimate antioxidative properties of extracts.
Fruiting body extracts of T.
versicolor and T.
gibbosa as well as T.
hirsuta extracts, except that at 20.0 mg/mL, were not genotoxic agents.
T.
versicolor extract had at 5.0 mg/mL the greatest antigenotoxic effect in both pre- and posttreatment of leukocytes.
The mycelium extracts of the three species had no genotoxic activity and significant antigenotoxic effect against H2O2-induced DNA damage, both in pre- and posttreatment.
The results suggest that extracts of these three species could be considered as strong antigenotoxic agents able to stimulate genoprotective response of cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Knežević, Aleksandar& Živković, Lada& Stajić, Mirjana& Vukojević, Jelena& Milovanović, Ivan& Spremo-Potparević, Biljana. 2015. Antigenotoxic Effect of Trametes spp. Extracts against DNA Damage on Human Peripheral White Blood Cells. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1078491
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Knežević, Aleksandar…[et al.]. Antigenotoxic Effect of Trametes spp. Extracts against DNA Damage on Human Peripheral White Blood Cells. The Scientific World Journal No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1078491
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Knežević, Aleksandar& Živković, Lada& Stajić, Mirjana& Vukojević, Jelena& Milovanović, Ivan& Spremo-Potparević, Biljana. Antigenotoxic Effect of Trametes spp. Extracts against DNA Damage on Human Peripheral White Blood Cells. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1078491
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078491
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر