Analysis of Japanese Patients Treated with or without Long-Term Epirubicin Plus Ara-C Intravesical Instillation Therapy for Low-Grade Superficial Bladder Cancer
المؤلفون المشاركون
Kato, Tomonori
Nomura, Kazushi
Wakisaka, Masami
Komiya, Akira
Kondo, Fukuo
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-21
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
The high incidence of tumor recurrence following transurethral resection (TUR) represents a major problem encountered in the management of bladder cancer.
This study examined the efficacy of intravesical chemotherapy in superficial bladder cancer.
We retrospectively analyzed 90 Japanese cases with low-grade superficial transitional cell carcinoma (stage T1, grades 1 and 2) who were rendered tumor-free by TURBT (TUR of bladder tumor) and who thereafter were treated with or without intravesical chemotherapy.
Among them, instillation was terminated in 2 patients due to adverse effects (severe but reversible chemical cystitis).
Remaining 88 patients were divided into 2 groups according to therapy: the TURBT-only group (n=46), defined as patients treated with TURBT alone, and the Instillation group (n=42), defined as patients treated with weekly intravesical instillation therapies using epirubicin plus Ara-C.
Recurrence-free rate was significantly higher in the Instillation group than in the TURBT-only group (p=0.02, HR = 0.457).
The 5-year recurrence-free rate was 58.5% for the Instillation group and 38.6% for the TURBT-only group.
Our instillation schedule represents the most intensive regimen among previously reported therapies and resulted in a 54.3% decrease in incidence of tumor recurrence.
We believe that the results of this study could provide useful information on management of bladder cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kato, Tomonori& Nomura, Kazushi& Kondo, Fukuo& Wakisaka, Masami& Komiya, Akira. 2015. Analysis of Japanese Patients Treated with or without Long-Term Epirubicin Plus Ara-C Intravesical Instillation Therapy for Low-Grade Superficial Bladder Cancer. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1078672
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kato, Tomonori…[et al.]. Analysis of Japanese Patients Treated with or without Long-Term Epirubicin Plus Ara-C Intravesical Instillation Therapy for Low-Grade Superficial Bladder Cancer. The Scientific World Journal No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1078672
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kato, Tomonori& Nomura, Kazushi& Kondo, Fukuo& Wakisaka, Masami& Komiya, Akira. Analysis of Japanese Patients Treated with or without Long-Term Epirubicin Plus Ara-C Intravesical Instillation Therapy for Low-Grade Superficial Bladder Cancer. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1078672
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078672
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر