![](/images/graphics-bg.png)
Effects of TGF-β1 on OPGRANKL Expression of Cementoblasts and Osteoblasts Are Similar without Stress but Different with Mechanical Compressive Stress
المؤلفون المشاركون
Yang, Xianrui
Wang, Yanmin
Han, Xianglong
Shu, Rui
Chen, Tian
Zeng, Huan
Xu, Xin
Huang, Lan
Ren, Aishu
Song, Jinlin
Cao, Li
Bai, Ding
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-15
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Introduction.
This study aimed to explore the effects of TGF-β1 on regulating activities of cementoblasts and osteoblasts with or without stress.
Material and Methods.
Human recombinant TGF-β1 was added with different doses.
Immunohistochemical test of osteoprotegerin (OPG)/receptor activator of nuclear factor-kappaB ligand (RANKL) and Alizarin Red-S staining were conducted.
Mechanical compressive stress was obtained by increasing the pressure of gaseous phase.
OPG/RANKL expression was detected in both cells through quantitative real-time PCR.
Results.
Similar significant differences ( P < 0.05 ) existed in OPG/RANKL change with increasing concentration of TGF-β1 without mechanical stress for cementoblasts and osteoblasts.
However, under 3 h stress, OPG increased and RANKL decreased significantly ( P < 0.01 ) but with similar OPG/RANKL change.
Moreover, under 24 h stress, OPG change exhibited no difference ( P > 0.05 ), but RANKL decreased significantly ( P < 0.01 ) at 10 and 100 ng/mL TGF-β1 in cementoblasts.
In osteoblasts, OPG increased significantly ( P < 0.01 ) at 10 and 100 ng/mL, whereas RANKL decreased with statistical difference ( P < 0.05 ) at 1 and 10 ng/mL.
Conclusions.
The effects of TGF-β1 on OPG/RANKL expression of cementoblasts and osteoblasts are similar even without mechanical stress.
However, these effects are different under mechanical compressive stress.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Xianrui& Wang, Yanmin& Han, Xianglong& Shu, Rui& Chen, Tian& Zeng, Huan…[et al.]. 2015. Effects of TGF-β1 on OPGRANKL Expression of Cementoblasts and Osteoblasts Are Similar without Stress but Different with Mechanical Compressive Stress. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1079039
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Xianrui…[et al.]. Effects of TGF-β1 on OPGRANKL Expression of Cementoblasts and Osteoblasts Are Similar without Stress but Different with Mechanical Compressive Stress. The Scientific World Journal No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1079039
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Xianrui& Wang, Yanmin& Han, Xianglong& Shu, Rui& Chen, Tian& Zeng, Huan…[et al.]. Effects of TGF-β1 on OPGRANKL Expression of Cementoblasts and Osteoblasts Are Similar without Stress but Different with Mechanical Compressive Stress. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1079039
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1079039
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)