The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study
المؤلفون المشاركون
Colombo, Delia
Abbruzzese, Giovanni
Barone, Paolo
Franconi, Flavia
Attar, Mahmood
Zagni, Emanuela
Haggiag, Shalom
Stocchi, Fabrizio
Antonini, Angelo
Simoni, Lucia
Bellia, Gilberto
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-20
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Background.
The early detection of wearing-off in Parkinson disease (DEEP) observational study demonstrated that women with Parkinson’s disease (PD) carry an increased risk (80.1%) for wearing-off (WO).
This post hoc analysis of DEEP study evaluates gender differences on WO and associated phenomena.
Methods.
Patients on dopaminergic treatment for ≥1 year were included in this multicenter observational cross-sectional study.
In a single visit, WO was diagnosed based on neurologist assessment as well as the use of the 19-item wearing-off questionnaire (WOQ-19); WO was defined for scores ≥2.
Post hoc analyses were conducted to investigate gender difference for demographic and clinical features with respect to WO.
Results.
Of 617 patients enrolled, 236 were women and 381 were men.
Prevalence of WO was higher among women, according to both neurologists’ judgment (61.9% versus 53.8%, P = 0.045 ) and the WOQ-19 analysis (72.5% versus 64.0%, P = 0.034 ).
In patients with WO (WOQ-19), women experienced ≥1 motor symptom in 72.5% versus 64.0% in men and ≥1 nonmotor symptom in 44.5% versus 36.7%, in men.
Conclusions.
Our results suggest WO as more common among women, for both motor and nonmotor symptoms.
Prospective studies are warranted to investigate this potential gender-effect.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Colombo, Delia& Abbruzzese, Giovanni& Antonini, Angelo& Barone, Paolo& Bellia, Gilberto& Franconi, Flavia…[et al.]. 2015. The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1079146
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Colombo, Delia…[et al.]. The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study. The Scientific World Journal No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1079146
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Colombo, Delia& Abbruzzese, Giovanni& Antonini, Angelo& Barone, Paolo& Bellia, Gilberto& Franconi, Flavia…[et al.]. The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1079146
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1079146
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر