In Vitro Evaluation of the Antimicrobial Ability and Cytotoxicity on Two Melanoma Cell Lines of a Benzylamide Derivative of Maslinic Acid
المؤلفون المشاركون
Danciu, Corina
Dehelean, Cristina
Muntean, Danina M.
Pavel, Ioana Zinuca
Oprean, Camelia
Muntean, Delia
Csuk, René
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Maslinic acid is a pentacyclic triterpene extracted from olives that has been systematically reported to exert several therapeutic effects, such as antitumoral, antidiabetic, antioxidant, anti-inflammatory, antiparasitic, and antiviral properties.
Recently, new derivatives of maslinic acid have been obtained and expanded the spectrum of biological activities and improved the existing ones.
The present study was meant to perform the in vitro assessment of the (i) cytotoxic effects of a benzylamide derivative of maslinic acid (“EM2”) (benzyl (2α, 3β) 2,3-diacetoxy-olean-12-en-28-amide) on B164A5 murine melanoma and A375 human malignant melanoma cell lines and the (ii) antimicrobial activity of the compound on several bacterial strains, respectively.
We obtained a dose-dependent cytotoxic effect of EM2 that was particularly relevant to the murine cell line.
As on the antibacterial activity, EM2 was tested on 10 bacterial strains Bacillus cereus, Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Enterococcus faecalis, Escherichia coli, Yersinia enterocolitica, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa and one fungus Candida albicans.
A significant antimicrobial effect was recorded for Streptococcus pyogenes and Staphylococcus aureus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pavel, Ioana Zinuca& Danciu, Corina& Oprean, Camelia& Dehelean, Cristina& Muntean, Delia& Csuk, René…[et al.]. 2016. In Vitro Evaluation of the Antimicrobial Ability and Cytotoxicity on Two Melanoma Cell Lines of a Benzylamide Derivative of Maslinic Acid. Analytical Cellular Pathology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1094958
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pavel, Ioana Zinuca…[et al.]. In Vitro Evaluation of the Antimicrobial Ability and Cytotoxicity on Two Melanoma Cell Lines of a Benzylamide Derivative of Maslinic Acid. Analytical Cellular Pathology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1094958
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pavel, Ioana Zinuca& Danciu, Corina& Oprean, Camelia& Dehelean, Cristina& Muntean, Delia& Csuk, René…[et al.]. In Vitro Evaluation of the Antimicrobial Ability and Cytotoxicity on Two Melanoma Cell Lines of a Benzylamide Derivative of Maslinic Acid. Analytical Cellular Pathology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1094958
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1094958
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر