The Effect of Esmolol on Tissue Perfusion and Clinical Prognosis of Patients with Severe Sepsis: A Prospective Cohort Study
المؤلفون المشاركون
Shang, Xiuling
Wang, Kaiyu
Xu, Jingqing
Gong, Shurong
Ye, Yong
Chen, Kaihua
Lian, Fayang
Chen, Wei
Yu, Rongguo
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Purpose.
This study was aimed at investigating the effect of esmolol on tissue perfusion and the clinical prognosis of patients with severe sepsis.
Materials and Methods.
One hundred fifty-one patients with severe sepsis were selected and divided into the esmolol group ( n = 75 ) or the control group ( n = 76 ), who received conventional antiseptic shock treatment.
The esmolol group received a continuous infusion of esmolol via a central venous catheter, and their heart rate (HR) was maintained at 70–100 bpm over 72 hours.
Results.
The HR of all patients reached the target level within 72 hours of treatment for both groups.
The effect of esmolol on PvaCO2 was only significant at 48 hours ( P < 0.05 ).
ScvO2 increased in the esmolol group and decreased in the control group ( P < 0.01 ).
Lac showed a linear downward trend over the treatment time, but the reduction was more significant in the control group at 48 hours ( P < 0.05 ) between the two groups.
Kaplan-Meier analysis showed a significantly shorter duration of mechanical ventilation in the esmolol group than in the control group ( P < 0.05 ).
Conclusions.
Esmolol reduced the duration of mechanical ventilation in patients with severe sepsis, with no significant effect on circulatory function or tissue perfusion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shang, Xiuling& Wang, Kaiyu& Xu, Jingqing& Gong, Shurong& Ye, Yong& Chen, Kaihua…[et al.]. 2016. The Effect of Esmolol on Tissue Perfusion and Clinical Prognosis of Patients with Severe Sepsis: A Prospective Cohort Study. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096812
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shang, Xiuling…[et al.]. The Effect of Esmolol on Tissue Perfusion and Clinical Prognosis of Patients with Severe Sepsis: A Prospective Cohort Study. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1096812
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shang, Xiuling& Wang, Kaiyu& Xu, Jingqing& Gong, Shurong& Ye, Yong& Chen, Kaihua…[et al.]. The Effect of Esmolol on Tissue Perfusion and Clinical Prognosis of Patients with Severe Sepsis: A Prospective Cohort Study. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096812
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1096812
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر