Fabrication of Poly( ε -caprolactone) Scaffolds Reinforced with Cellulose Nanofibers, with and without the Addition of Hydroxyapatite Nanoparticles
المؤلفون المشاركون
Morouço, Pedro G.
Biscaia, Sara
Viana, Tânia
Franco, Margarida
Malça, Cândida
Mateus, Artur
Moura, Carla
Ferreira, Frederico C.
Mitchell, Geoffrey
Alves, Nuno M.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Biomaterial properties and controlled architecture of scaffolds are essential features to provide an adequate biological and mechanical support for tissue regeneration, mimicking the ingrowth tissues.
In this study, a bioextrusion system was used to produce 3D biodegradable scaffolds with controlled architecture, comprising three types of constructs: (i) poly(ε-caprolactone) (PCL) matrix as reference; (ii) PCL-based matrix reinforced with cellulose nanofibers (CNF); and (iii) PCL-based matrix reinforced with CNF and hydroxyapatite nanoparticles (HANP).
The effect of the addition and/or combination of CNF and HANP into the polymeric matrix of PCL was investigated, with the effects of the biomaterial composition on the constructs (morphological, thermal, and mechanical performances) being analysed.
Scaffolds were produced using a single lay-down pattern of 0/90°, with the same processing parameters among all constructs being assured.
The performed morphological analyses showed a satisfactory distribution of CNF within the polymer matrix and high reliability was obtained among the produced scaffolds.
Significant effects on surface wettability and thermal properties were observed, among scaffolds.
Regarding the mechanical properties, higher scaffold stiffness in the reinforced scaffolds was obtained.
Results from the cytotoxicity assay suggest that all the composite scaffolds presented good biocompatibility.
The results of this first study on cellulose and hydroxyapatite reinforced constructs with controlled architecture clearly demonstrate the potential of these 3D composite constructs for cell cultivation with enhanced mechanical properties.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Morouço, Pedro G.& Biscaia, Sara& Viana, Tânia& Franco, Margarida& Malça, Cândida& Mateus, Artur…[et al.]. 2016. Fabrication of Poly( ε -caprolactone) Scaffolds Reinforced with Cellulose Nanofibers, with and without the Addition of Hydroxyapatite Nanoparticles. BioMed Research International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1096917
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Morouço, Pedro G.…[et al.]. Fabrication of Poly( ε -caprolactone) Scaffolds Reinforced with Cellulose Nanofibers, with and without the Addition of Hydroxyapatite Nanoparticles. BioMed Research International No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1096917
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Morouço, Pedro G.& Biscaia, Sara& Viana, Tânia& Franco, Margarida& Malça, Cândida& Mateus, Artur…[et al.]. Fabrication of Poly( ε -caprolactone) Scaffolds Reinforced with Cellulose Nanofibers, with and without the Addition of Hydroxyapatite Nanoparticles. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1096917
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1096917
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر