Soft Tissue Augmentation with Autologous Platelet Gel and β -TCP: A Histologic and Histometric Study in Mice
المؤلفون المشاركون
Scarano, A.
Ceccarelli, Maurizio
Marchetti, Massimiliano
Mortellaro, Carmen
Piattelli, Adriano
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Facial aging is a dynamic process involving both soft tissue and bony structures.
Skin atrophy, with loss of tone, elasticity, and distribution of facial fat, coupled with gravity and muscle activity, leads to wrinkling and folds.
Purpose.
The aim of the study was to evaluate microporous tricalcium phosphate (β-TCP) and autologous platelet gel (APG) mix in mice for oral and maxillofacial soft tissue augmentation.
The hypothesis was that β-TCP added with APG was able to increase the biostimulating effect on fibroblasts and quicken resorption.
Materials and Methods.
Ten female, 6–8-week-old black-haired mice were selected.
β-TCP/APG gel was injected into one cheek; the other was used as control.
The animals were sacrificed at 8 weeks and histologically evaluated.
Results.
The new fibroblast was intensively stained with acid fuchsin and presented in contact with β-TCP.
At higher magnification, actively secreting fibroblasts were observed at the periphery of β-TCP with a well differentiated fibroblast cell line and blood vessels.
Acid fuchsin stained cutaneous structures in pink: no epidermal/dermal alterations or pathological inflammatory infiltrates were detected.
The margins of β-TCP granules were clear and not diffused near tissues.
Conclusion.
APG with β-TCP preserves skin morphology, without immune response, with an excellent tolerability and is a promising scaffold for cells and biomaterial for soft tissue augmentation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Scarano, A.& Ceccarelli, Maurizio& Marchetti, Massimiliano& Piattelli, Adriano& Mortellaro, Carmen. 2016. Soft Tissue Augmentation with Autologous Platelet Gel and β -TCP: A Histologic and Histometric Study in Mice. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097029
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Scarano, A.…[et al.]. Soft Tissue Augmentation with Autologous Platelet Gel and β -TCP: A Histologic and Histometric Study in Mice. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1097029
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Scarano, A.& Ceccarelli, Maurizio& Marchetti, Massimiliano& Piattelli, Adriano& Mortellaro, Carmen. Soft Tissue Augmentation with Autologous Platelet Gel and β -TCP: A Histologic and Histometric Study in Mice. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1097029
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097029
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر