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Percutaneous Transluminal Angioplasty in Patients with Peripheral Arterial Disease Does Not Affect Circulating Monocyte Subpopulations
المؤلفون المشاركون
Maga, Pawel
Partyka, Lukasz
Krzanowski, Marek
Malinowski, Krzysztof P.
Nizankowski, Rafal
Mikołajczyk, Tomasz
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-13
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Monocytes are mononuclear cells characterized by distinct morphology and expression of CD14 and CD16 surface receptors.
Classical, quiescent monocytes are positive for CD14 (lipopolysaccharide receptor) but do not express Fc gamma receptor III (CD16).
Intermediate monocytes coexpress CD16 and CD14.
Nonclassical monocytes with low expression of CD14 represent mature macrophage-like monocytes.
Monocyte behavior in peripheral arterial disease (PAD) and during vessel wall directed treatment is not well defined.
This observation study aimed at monitoring of acute changes in monocyte subpopulations during percutaneous transluminal angioplasty (PTA) in PAD patients.
Patients with Rutherford 3 and 4 PAD with no signs of inflammatory process underwent PTA of iliac, femoral, or popliteal segments.
Flow cytometry for CD14, CD16, HLA-DR, CD11b, CD11c, and CD45RA antigens allowed characterization of monocyte subpopulations in blood sampled before and after PTA (direct angioplasty catheter sampling).
Patients were clinically followed up for 12 months.
All 61 enrolled patients completed 12-month follow-up.
Target vessel failure occurred in 12 patients.
While absolute counts of monocyte were significantly lower after PTA, only subtle monocyte activation after PTA (CD45RA and β-integrins) occurred.
None of the monocyte parameters correlated with long-term adverse clinical outcome.
Changes in absolute monocyte counts and subtle changes towards an activation phenotype after PTA may reflect local cell adhesion phenomenon in patients with Rutherford 3 or 4 peripheral arterial disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maga, Pawel& Mikołajczyk, Tomasz& Partyka, Lukasz& Krzanowski, Marek& Malinowski, Krzysztof P.& Nizankowski, Rafal. 2016. Percutaneous Transluminal Angioplasty in Patients with Peripheral Arterial Disease Does Not Affect Circulating Monocyte Subpopulations. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1097139
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maga, Pawel…[et al.]. Percutaneous Transluminal Angioplasty in Patients with Peripheral Arterial Disease Does Not Affect Circulating Monocyte Subpopulations. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1097139
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maga, Pawel& Mikołajczyk, Tomasz& Partyka, Lukasz& Krzanowski, Marek& Malinowski, Krzysztof P.& Nizankowski, Rafal. Percutaneous Transluminal Angioplasty in Patients with Peripheral Arterial Disease Does Not Affect Circulating Monocyte Subpopulations. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1097139
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097139
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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