Genetic Structure and Drug Susceptibility Patterns of Mycobacterium tuberculosis Complex Strains Responsible of Human Pulmonary Tuberculosis in the Major Rearing Region in Cameroon
المؤلفون المشاركون
Eyangoh, Sara
Koro Koro, Francioli
Um Boock, Alphonse
Kaiyven, Afi Leslie
Noeske, Juergen
Gutierrez, Cristina
Kuaban, Christopher
Etoa, François-Xavier
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-29
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Cameroon this last decade continues to present a low contribution of M.
africanum and M.
bovis in human tuberculosis (TB), while M.
bovis was prevalent in cattle but all these pieces of information only concerned West and Center regions.
Methods.
We carried out the first study in Adamaoua, one of the most rearing regions of Cameroon, on the genetic structure and drug susceptibility of the MTBC strains isolated from newly diagnosed sputum smear-positive patients aged 15 years and above.
For that purpose, spoligotyping, a modified 15 standard MIRU/VNTR loci typing, and the proportion method were used.
Results.
Four hundred and thirty-seven MTBC isolates were analyzed by spoligotyping.
Of these, 423 were identified as M.
tuberculosis, within the Cameroon family being dominant with 278 (65.7%) isolates; twelve (2.75%) isolates were classified as M.
africanum and two as M.
bovis.
MIRU/VNTR typing of the most prevalent sublineage (SIT 61) suggested that this lineage is not a unique clone as thought earlier but could constitute a group of strains implicated to different pocket of TB transmission.
Only M.
tuberculosis sublineages were associated with antituberculosis drug resistance.
Conclusion.
These results showed the weak contribution of M.
africanum and M.
bovis to human active pulmonary tuberculosis in Cameroon even in the rearing region.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Koro Koro, Francioli& Um Boock, Alphonse& Kaiyven, Afi Leslie& Noeske, Juergen& Gutierrez, Cristina& Kuaban, Christopher…[et al.]. 2016. Genetic Structure and Drug Susceptibility Patterns of Mycobacterium tuberculosis Complex Strains Responsible of Human Pulmonary Tuberculosis in the Major Rearing Region in Cameroon. BioMed Research International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1097187
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Koro Koro, Francioli…[et al.]. Genetic Structure and Drug Susceptibility Patterns of Mycobacterium tuberculosis Complex Strains Responsible of Human Pulmonary Tuberculosis in the Major Rearing Region in Cameroon. BioMed Research International No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1097187
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Koro Koro, Francioli& Um Boock, Alphonse& Kaiyven, Afi Leslie& Noeske, Juergen& Gutierrez, Cristina& Kuaban, Christopher…[et al.]. Genetic Structure and Drug Susceptibility Patterns of Mycobacterium tuberculosis Complex Strains Responsible of Human Pulmonary Tuberculosis in the Major Rearing Region in Cameroon. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1097187
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097187
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر