Lack of Associations between XPC Gene Polymorphisms and Neuroblastoma Susceptibility in a Chinese Population
المؤلفون المشاركون
Zheng, Jintao
Zhang, Ruizhong
Zhu, Jinhong
Wang, Fenghua
Yang, Tianyou
He, Jing
Xia, Huimin
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-26
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Neuroblastoma is one of the most malignant solid tumors in infants and young children.
No more than 40% of neuroblastoma patients can survive for longer than five years after it has been diagnosed.
XPC protein is a pivotal factor that recognizes DNA damage and starts up the nucleotide excision repair (NER) in mammalian cells.
This makes up the first group to defend against the cancer.
Previous studies have identified that XPC gene polymorphisms were associated with various types of cancer.
However, the associations between XPC gene polymorphisms and neuroblastoma risk have not yet been studied.
We investigated the associations between three XPC gene polymorphisms (rs2228001 A>C, rs2228000 C>T, and rs2229090 G>C) and neuroblastoma risk with 256 neuroblastoma patients and 531 healthy controls in a Chinese Han population.
Odds ratios and 95% confidence intervals were used to access the association between these three polymorphisms and neuroblastoma risk.
No significant association was detected between these three polymorphisms and neuroblastoma risk in the overall analysis as well as in the stratification analysis.
These results suggest that none of these three polymorphisms may be associated with the risk of neuroblastoma in the Chinese Han population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zheng, Jintao& Zhang, Ruizhong& Zhu, Jinhong& Wang, Fenghua& Yang, Tianyou& He, Jing…[et al.]. 2016. Lack of Associations between XPC Gene Polymorphisms and Neuroblastoma Susceptibility in a Chinese Population. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097196
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zheng, Jintao…[et al.]. Lack of Associations between XPC Gene Polymorphisms and Neuroblastoma Susceptibility in a Chinese Population. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097196
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zheng, Jintao& Zhang, Ruizhong& Zhu, Jinhong& Wang, Fenghua& Yang, Tianyou& He, Jing…[et al.]. Lack of Associations between XPC Gene Polymorphisms and Neuroblastoma Susceptibility in a Chinese Population. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097196
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097196
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر