Proteomic Analysis of Stage-II Breast Cancer from Formalin-Fixed Paraffin-Embedded Tissues
المؤلفون المشاركون
Valan Arasu, Mariadhas
Abdullah Al-Dhabi, Naif
Ilavenil, Soundharrajan
Choi, Ki Choon
Srigopalram, Srisesharam
Kim, Young Ock
Agastian, Paul
Baaru, Rajasekhar
Balamurugan, Kannan
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Breast cancer is the most frequently occurring disease among women worldwide.
The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures.
Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, gene expression pattern alone is not sufficient to predict the exact mechanisms.
Current proteomics tools hold great application for analysis of cancerous conditions.
Hence, the generation of differential protein expression profiles has been optimized for breast cancer and normal tissue samples in our organization.
Normal and tumor tissues were collected from 20 people from a local hospital.
Proteins from the diseased and normal tissues have been investigated by 2D gel electrophoresis and MALDI-TOF-MS.
The peptide mass fingerprint data were fed into various public domains like Mascot, MS-Fit, and Pept-ident against Swiss-Prot protein database and the proteins of interest were identified.
Some of the differentially expressed proteins identified were human annexin, glutathione S-transferase, vimentin, enolase-1, dihydrolipoamide dehydrogenase, glutamate dehydrogenase, Cyclin A1, hormone sensitive lipase, beta catenin, and so forth.
Many types of proteins were identified as fundamental steps for developing molecular markers for diagnosis of human breast cancer as well as making a new proteomic database for future research.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdullah Al-Dhabi, Naif& Srigopalram, Srisesharam& Ilavenil, Soundharrajan& Kim, Young Ock& Agastian, Paul& Baaru, Rajasekhar…[et al.]. 2016. Proteomic Analysis of Stage-II Breast Cancer from Formalin-Fixed Paraffin-Embedded Tissues. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097226
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdullah Al-Dhabi, Naif…[et al.]. Proteomic Analysis of Stage-II Breast Cancer from Formalin-Fixed Paraffin-Embedded Tissues. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097226
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdullah Al-Dhabi, Naif& Srigopalram, Srisesharam& Ilavenil, Soundharrajan& Kim, Young Ock& Agastian, Paul& Baaru, Rajasekhar…[et al.]. Proteomic Analysis of Stage-II Breast Cancer from Formalin-Fixed Paraffin-Embedded Tissues. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097226
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097226
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر