Pathological Predictors of Shunt Stenosis and Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt

المؤلفون المشاركون

He, Fuliang
Dai, Shan
Xiao, Zhibo
Wang, Lei
Yue, Zhendong
Zhao, Hongwei
Zhao, Mengfei
Lin, Qiushi
Dong, Xiaoqun
Liu, Fuquan

المصدر

BioMed Research International

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-11-15

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الطب البشري

الملخص EN

Background.

Transjugular intrahepatic portosystemic shunt (TIPS) is an artificial channel from the portal vein to the hepatic vein or vena cava for controlling portal vein hypertension.

The major drawbacks of TIPS are shunt stenosis and hepatic encephalopathy (HE); previous studies showed that post-TIPS shunt stenosis and HE might be correlated with the pathological features of the liver tissues.

Therefore, we analyzed the pathological predictors for clinical outcome, to determine the risk factors for shunt stenosis and HE after TIPS.

Methods.

We recruited 361 patients who suffered from portal hypertension symptoms and were treated with TIPS from January 2009 to December 2012.

Results.

Multivariate logistic regression analysis showed that the risk of shunt stenosis was increased with more severe inflammation in the liver tissue (OR, 2.864; 95% CI: 1.466–5.592; P=0.002), HE comorbidity (OR, 6.266; 95% CI, 3.141–12.501; P<0.001), or higher MELD score (95% CI, 1.298–1.731; P<0.001).

Higher risk of HE was associated with shunt stenosis comorbidity (OR, 6.266; 95% CI, 3.141–12.501; P<0.001), higher stage of the liver fibrosis (OR, 2.431; 95% CI, 1.355–4.359; P=0.003), and higher MELD score (95% CI, 1.711–2.406; P<0.001).

Conclusion.

The pathological features can predict individual susceptibility to shunt stenosis and HE.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

He, Fuliang& Dai, Shan& Xiao, Zhibo& Wang, Lei& Yue, Zhendong& Zhao, Hongwei…[et al.]. 2016. Pathological Predictors of Shunt Stenosis and Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1097403

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

He, Fuliang…[et al.]. Pathological Predictors of Shunt Stenosis and Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1097403

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

He, Fuliang& Dai, Shan& Xiao, Zhibo& Wang, Lei& Yue, Zhendong& Zhao, Hongwei…[et al.]. Pathological Predictors of Shunt Stenosis and Hepatic Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1097403

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1097403