Differential Proteomics Analysis of Colonic Tissues in Patients of Slow Transit Constipation
المؤلفون المشاركون
Wan, Songlin
Liu, Weicheng
Tian, Cuiping
Ren, Xianghai
Ding, Zhao
Qian, Qun
Jiang, Congqing
Wu, Yunhua
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To investigate and screen the different expression of proteins in STC and normal group with a comparative proteomic approach.
Methods.
Two-dimensional electrophoresis was applied to separate the proteins in specimens from both 5 STC patients and 5 normal controls.
The proteins with statistically significant differential expression between two groups were identified by computer aided image analysis and matrix assisted laser desorption ionization tandem time of flight mass spectrometry (MALDI-TOF-MS).
Results.
A total of 239 protein spots were identified in the average gel of the normal control and 215 in patients with STC.
A total of 197 protein spots were matched and the mean matching rate was 82%.
There were 14 protein spots which were expressed with statistically significant differences from others.
Of those 14 protein spots, the expression of 12 spots increased markedly, while that of 2 spots decreased significantly.
Conclusion.
The proteomics expression in colonic specimens of STC patients is statistically significantly different from that of normal control, which may be associated with the pathogenesis of STC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wan, Songlin& Liu, Weicheng& Tian, Cuiping& Ren, Xianghai& Ding, Zhao& Qian, Qun…[et al.]. 2016. Differential Proteomics Analysis of Colonic Tissues in Patients of Slow Transit Constipation. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097895
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wan, Songlin…[et al.]. Differential Proteomics Analysis of Colonic Tissues in Patients of Slow Transit Constipation. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1097895
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wan, Songlin& Liu, Weicheng& Tian, Cuiping& Ren, Xianghai& Ding, Zhao& Qian, Qun…[et al.]. Differential Proteomics Analysis of Colonic Tissues in Patients of Slow Transit Constipation. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1097895
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1097895
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر