Lack of an Association between Neutrophil-to-Lymphocyte Ratio and PSA Failure of Prostate Cancer Patients Who Underwent Radical Prostatectomy
المؤلفون المشاركون
Miyamoto, Hiroshi
Miyoshi, Yasuhide
Teranishi, Jun-ichi
Yao, Masahiro
Uemura, Hiroji
Maeda, Yoko
Koizumi, Mitsuyuki
Kumano, Yohei
Ohtaka, Mari
Kondo, Takuya
Mochizuki, Taku
Hattori, Yusuke
Yumura, Yasushi
Ito, Hiroki
Kawahara, Takashi
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
The neutrophil-to-lymphocyte ratio (NLR), which can be easily calculated from routine complete blood counts of the peripheral blood, has been suggested to serve as a prognostic factor for some solid malignancies.
In the present study, we aimed to determine the relationship between NLR in prostate cancer patients undergoing radical prostatectomy (RP) and their prognosis.
Materials and Methods.
We assessed NLR in 73 men (patients) who received RP for their prostate cancer.
We also performed immunohistochemistry for CD8 and CD66b in a separate set of RP specimens.
Results.
The median NLR in the 73 patients was 1.85.
There were no significant correlations of NLR with tumor grade (p=0.834), pathological T stage (p=0.082), lymph node metastasis (p=0.062), or resection margin status (p=0.772).
Based on the area under the receiver operator characteristic curve (AUROC) to predict biochemical recurrence after RP, potential NLR cut-off point was determined to be 2.88 or 3.88.
However, both of these cut-off points did not precisely predict the prognosis.
There were no statistically significant differences in the number of CD66b-positive neutrophils or CD8-positive lymphocytes between stromal tissues adjacent to cancer glands and stromal tissues away from cancer glands and between different grades or stages of tumors.
Conclusions.
There was no association between NLR and biochemical failure after prostatectomy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maeda, Yoko& Kawahara, Takashi& Koizumi, Mitsuyuki& Ito, Hiroki& Kumano, Yohei& Ohtaka, Mari…[et al.]. 2016. Lack of an Association between Neutrophil-to-Lymphocyte Ratio and PSA Failure of Prostate Cancer Patients Who Underwent Radical Prostatectomy. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098406
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maeda, Yoko…[et al.]. Lack of an Association between Neutrophil-to-Lymphocyte Ratio and PSA Failure of Prostate Cancer Patients Who Underwent Radical Prostatectomy. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098406
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maeda, Yoko& Kawahara, Takashi& Koizumi, Mitsuyuki& Ito, Hiroki& Kumano, Yohei& Ohtaka, Mari…[et al.]. Lack of an Association between Neutrophil-to-Lymphocyte Ratio and PSA Failure of Prostate Cancer Patients Who Underwent Radical Prostatectomy. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098406
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098406
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر