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Growing Menace of Antibacterial Resistance in Clinical Isolates of Pseudomonas aeruginosa in Nepal: An Insight of Beta-Lactamase Production
المؤلفون المشاركون
Ansari, Shamshul
Gautam, Rajendra
Shrestha, Sony
Thapa, Sangita
Dhital, Rabindra
Puri, Ram
Chaudhary, Niraj
Khatiwada, Suresh
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Pseudomonas aeruginosa is the most frequently isolated organism as it acts as the opportunistic pathogen and can cause infections in immunosuppressed patients.
The production of different types of beta-lactamases renders this organism resistant to many commonly used antimicrobials.
Therefore, the aim of this study was to document the antibiotic resistance rate in Pseudomonas aeruginosa isolated from different clinical specimens.
Methods.
Pseudomonas aeruginosa recovered was identified by standard microbiological methods.
Antibiotic susceptibility testing was performed by modified Kirby-Bauer disc diffusion method following Clinical and Laboratory Standard Institute (CLSI) guidelines and all the suspected isolates were tested for the production of ESBLs, MBLs, and AmpC.
Results.
Out of total (178) isolates, 83.1% were recovered from the inpatient department (IPD).
Majority of the isolates mediated resistance towards the beta-lactam antibiotics, while nearly half of the isolates were resistant to ciprofloxacin.
Most of the aminoglycosides used showed resistance rate up to 75% but amikacin proved to be better option.
No resistance to polymyxin was observed.
ESBLs, MBLs, and AmpC mediated resistance was seen in 33.1%, 30.9%, and 15.7% isolates, respectively.
Conclusions.
Antibiotic resistance rate and beta-lactamase mediated resistance were high.
Thus, regular surveillance of drug resistance is of utmost importance.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ansari, Shamshul& Dhital, Rabindra& Shrestha, Sony& Thapa, Sangita& Puri, Ram& Chaudhary, Niraj…[et al.]. 2016. Growing Menace of Antibacterial Resistance in Clinical Isolates of Pseudomonas aeruginosa in Nepal: An Insight of Beta-Lactamase Production. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098476
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ansari, Shamshul…[et al.]. Growing Menace of Antibacterial Resistance in Clinical Isolates of Pseudomonas aeruginosa in Nepal: An Insight of Beta-Lactamase Production. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098476
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ansari, Shamshul& Dhital, Rabindra& Shrestha, Sony& Thapa, Sangita& Puri, Ram& Chaudhary, Niraj…[et al.]. Growing Menace of Antibacterial Resistance in Clinical Isolates of Pseudomonas aeruginosa in Nepal: An Insight of Beta-Lactamase Production. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098476
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098476
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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