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Diagnostic Value of White Blood Cell and C-Reactive Protein in Pediatric Appendicitis
المؤلفون المشاركون
Buyukbese Sarsu, Sevgi
Sarac, Fatma
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Acute appendicitis (AA) associated with acute phase reaction is the most prevalent disease which requires emergency surgery.
Its delayed diagnosis and unnecessarily performed appendectomies lead to numerous complications.
In our study, we aimed to detect the role of WBC and CRP in the exclusion of acute and complicated appendicitis and diagnostic accuracy in pediatric age group.
Methods.
Appendectomized patient groups were constructed based on the results of histological evaluation.
The area under a receiver operating characteristic (ROC) curve (AUC) was performed to examine diagnostic accuracy.
Results.
When WBC and CRP were used in combination, based on cut-off values of ≥13.1 × 103/μL for WBC counts and ≥1.17 mg/dL for CRP level, diagnostic parameters were as follows: sensitivity, 98.7%; specificity, 71.3%; PPV, 50.6%; NPV, 99.5%; diagnostic accuracy, 77.6%; LR(+), 3.44; LR(−), 0.017.
AUC values were 0.845 (95% CI 0.800–0.891) for WBC and 0.887 (95% CI 0.841–0.932) for CRP.
Conclusions.
For complicated appendicitis, CRP has the highest degree of diagnostic accuracy.
The diagnosis of appendicitis should be made primarily based on clinical examination, and obviously more specific and systemic inflammatory markers are needed.
Combined use of cut-off values of WBC (≥13100/μL) and CRP (≥1.17 mg/L) yields a higher sensitivity and NPV for the diagnosis of complicated appendicitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Buyukbese Sarsu, Sevgi& Sarac, Fatma. 2016. Diagnostic Value of White Blood Cell and C-Reactive Protein in Pediatric Appendicitis. BioMed Research International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098506
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Buyukbese Sarsu, Sevgi& Sarac, Fatma. Diagnostic Value of White Blood Cell and C-Reactive Protein in Pediatric Appendicitis. BioMed Research International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1098506
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Buyukbese Sarsu, Sevgi& Sarac, Fatma. Diagnostic Value of White Blood Cell and C-Reactive Protein in Pediatric Appendicitis. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1098506
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098506
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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