Effect of Extracellular Matrix Membrane on Bone Formation in a Rabbit Tibial Defect Model
المؤلفون المشاركون
Lee, Jong-Ho
Kim, Sungtae
Hwang, Jin Wook
Kim, Se Won
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Absorbable extracellular matrix (ECM) membrane has recently been used as a barrier membrane (BM) in guided tissue regeneration (GTR) and guided bone regeneration (GBR).
Absorbable BMs are mostly based on collagen, which is more biocompatible than synthetic materials.
However, implanted absorbable BMs can be rapidly degraded by enzymes in vivo.
In a previous study, to delay degradation time, collagen fibers were treated with cross-linking agents.
These compounds prevented the enzymatic degradation of BMs.
However, cross-linked BMs can exhibit delayed tissue integration.
In addition, the remaining cross-linker could induce inflammation.
Here, we attempted to overcome these problems using a natural ECM membrane.
The membrane consisted of freshly harvested porcine pericardium that was stripped from cells and immunoreagents by a cleaning process.
Acellular porcine pericardium (APP) showed a bilayer structure with a smooth upper surface and a significantly coarser bottom layer.
APP is an ECM with a thin layer (0.18–0.35 mm) but with excellent mechanical properties.
Tensile strength of APP was 14.15±2.24 MPa.
In in vivo experiments, APP was transplanted into rabbit tibia.
The biocompatible material was retained for up to 3 months without the need for cross-linking.
Therefore, we conclude that APP could support osteogenesis as a BM for up to 3 months.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hwang, Jin Wook& Kim, Sungtae& Kim, Se Won& Lee, Jong-Ho. 2016. Effect of Extracellular Matrix Membrane on Bone Formation in a Rabbit Tibial Defect Model. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098529
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hwang, Jin Wook…[et al.]. Effect of Extracellular Matrix Membrane on Bone Formation in a Rabbit Tibial Defect Model. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098529
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hwang, Jin Wook& Kim, Sungtae& Kim, Se Won& Lee, Jong-Ho. Effect of Extracellular Matrix Membrane on Bone Formation in a Rabbit Tibial Defect Model. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098529
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098529
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر