A Comparison of Surgical Invasions for Spinal Nerve Ligation with or without Paraspinal Muscle Removal in a Rat Neuropathic Pain Model
المؤلفون المشاركون
Huang, Yi-Gang
Zhang, Qing
Wu, Hao
Zhang, Chang-Qing
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
L5 spinal nerve ligation (SNL) in rats is one of the most popular models for studying neuropathic pain because of its high reproducibility.
During the surgery, a part of the L5 paraspinal muscle is usually removed, which produces extra trauma and may potentially affect the physiological processes involved in neuropathic pain.
To reduce the surgical trauma, the paraspinal muscle retraction was developed for exposure of the spinal nerve.
The current study was aimed at comparing the surgical invasions between the L5 SNL models with paraspinal muscle removal or retraction.
The results showed that both methods induced similar neuropathic pain behavior.
However, the paraspinal muscle retraction group exhibited an average of 2.7 mg less blood loss than the muscle removal group.
This group also showed a significantly lower increase in serum myoglobin and creatine phosphokinase levels on postoperative days 1 and 2, as well as a lower increase in interleukin-1β and interleukin-6 levels on postoperative day 1.
The paraspinal muscle maintained normal morphological features following paraspinal muscle retraction.
Our results indicate that the SNL rat model with paraspinal muscle retraction is a reliable physiological model that is reproducible, readily available, and less invasive than the model with muscle removal.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Yi-Gang& Zhang, Qing& Wu, Hao& Zhang, Chang-Qing. 2016. A Comparison of Surgical Invasions for Spinal Nerve Ligation with or without Paraspinal Muscle Removal in a Rat Neuropathic Pain Model. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098534
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Yi-Gang…[et al.]. A Comparison of Surgical Invasions for Spinal Nerve Ligation with or without Paraspinal Muscle Removal in a Rat Neuropathic Pain Model. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098534
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Yi-Gang& Zhang, Qing& Wu, Hao& Zhang, Chang-Qing. A Comparison of Surgical Invasions for Spinal Nerve Ligation with or without Paraspinal Muscle Removal in a Rat Neuropathic Pain Model. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098534
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098534
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر