An Interoperability Platform Enabling Reuse of Electronic Health Records for Signal Verification Studies
المؤلفون المشاركون
Sinaci, A. Anil
Laleci Erturkmen, Gokce B.
Yuksel, Mustafa
Invernizzi, Paolo
Gonul, Suat
Facchinetti, Sara
Migliavacca, Andrea
Bergvall, Tomas
Depraetere, Kristof
De Roo, Jos
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-31
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
Depending mostly on voluntarily sent spontaneous reports, pharmacovigilance studies are hampered by low quantity and quality of patient data.
Our objective is to improve postmarket safety studies by enabling safety analysts to seamlessly access a wide range of EHR sources for collecting deidentified medical data sets of selected patient populations and tracing the reported incidents back to original EHRs.
We have developed an ontological framework where EHR sources and target clinical research systems can continue using their own local data models, interfaces, and terminology systems, while structural interoperability and Semantic Interoperability are handled through rule-based reasoning on formal representations of different models and terminology systems maintained in the SALUS Semantic Resource Set.
SALUS Common Information Model at the core of this set acts as the common mediator.
We demonstrate the capabilities of our framework through one of the SALUS safety analysis tools, namely, the Case Series Characterization Tool, which have been deployed on top of regional EHR Data Warehouse of the Lombardy Region containing about 1 billion records from 16 million patients and validated by several pharmacovigilance researchers with real-life cases.
The results confirm significant improvements in signal detection and evaluation compared to traditional methods with the missing background information.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yuksel, Mustafa& Gonul, Suat& Laleci Erturkmen, Gokce B.& Sinaci, A. Anil& Invernizzi, Paolo& Facchinetti, Sara…[et al.]. 2016. An Interoperability Platform Enabling Reuse of Electronic Health Records for Signal Verification Studies. BioMed Research International،Vol. 2016, no. 2016, pp.1-18.
https://search.emarefa.net/detail/BIM-1098536
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yuksel, Mustafa…[et al.]. An Interoperability Platform Enabling Reuse of Electronic Health Records for Signal Verification Studies. BioMed Research International No. 2016 (2016), pp.1-18.
https://search.emarefa.net/detail/BIM-1098536
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yuksel, Mustafa& Gonul, Suat& Laleci Erturkmen, Gokce B.& Sinaci, A. Anil& Invernizzi, Paolo& Facchinetti, Sara…[et al.]. An Interoperability Platform Enabling Reuse of Electronic Health Records for Signal Verification Studies. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-18.
https://search.emarefa.net/detail/BIM-1098536
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098536
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر