Virological and Immunological Status of the People Living with HIVAIDS Undergoing ART Treatment in Nepal
المؤلفون المشاركون
Ojha, Chet Raj
Shakya, Geeta
Dumre, Shyam Prakash
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-28
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Antiretroviral therapy (ART) has increased the life span of the people living with HIV (PLHIV), but their virological and immunological outcomes are not well documented in Nepal.
The study was conducted at a tertiary care center including 826 HIV-1 seropositive individuals undergoing ART for at least six months.
Plasma viral load (HIV-1 RNA) was detected by Real Time PCR and CD4+ T-lymphocyte (CD4+) counts were estimated by flow cytometry.
The mean CD4+ count of patients was 501 (95% CI = 325–579) cells/cumm, but about 35% of patients had CD4+ T cell counts below 350 cells/cumm.
With increasing age, average CD4+ count was found to be decreasing ( p = 0.005 ).
Of the total cases, 82 (9.92%) were found to have virological failure (viral load: >1000 copies/ml).
Tenofovir/Lamivudine/Efavirenz (TDF/3TC/EFV), the frequently used ART regimen in Nepal, showed virological failure in 11.34% and immunological failure in 37.17% of patients.
Virological failure rate was higher among children < 15 years (14.5%) ( p = 0.03 ); however, no association was observed between ART outcomes and gender or route of transmission.
The study suggests there are still some chances of virological and immunological failures despite the success of highly active ART (HAART).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ojha, Chet Raj& Shakya, Geeta& Dumre, Shyam Prakash. 2016. Virological and Immunological Status of the People Living with HIVAIDS Undergoing ART Treatment in Nepal. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098587
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ojha, Chet Raj…[et al.]. Virological and Immunological Status of the People Living with HIVAIDS Undergoing ART Treatment in Nepal. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1098587
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ojha, Chet Raj& Shakya, Geeta& Dumre, Shyam Prakash. Virological and Immunological Status of the People Living with HIVAIDS Undergoing ART Treatment in Nepal. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1098587
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098587
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر