Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing
المؤلفون المشاركون
Metcalf, Daniel G.
Parsons, David
Meredith, Kate
Rowlands, Victoria J.
Short, Darryl
Bowler, Philip G.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-20
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Biofilm development in wounds is now acknowledged to be a precursor to infection and a cause of delayed healing.
A next-generation antibiofilm carboxymethylcellulose silver-containing wound dressing (NGAD) has been developed to disrupt and kill biofilm microorganisms.
This in vitro study aimed to compare its effectiveness against various existing wound dressings and examine its mode of action.
A number of biofilm models of increasing complexity were used to culture biofilms of wound-relevant pathogens, before exposure to test dressings.
Confocal microscopy, staining, and imaging of biofilm constituents, total viable counting, and elemental analysis were conducted to assess dressing antibiofilm performance.
Live/dead staining and viable counting of biofilms demonstrated that the NGAD was more effective at killing biofilm bacteria than two other standard silver dressings.
Staining of biofilm polysaccharides showed that the NGAD was also more effective at reducing this protective biofilm component than standard silver dressings, and image analyses confirmed the superior biofilm killing and removal performance of the NGAD.
The biofilm-disruptive and silver-enhancing modes of action of the NGAD were supported by significant differences (p<0.05) in biofilm elemental markers and silver donation.
This in vitro study improves our understanding of how antibiofilm dressing technology can be effective against the challenge of biofilm.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Parsons, David& Meredith, Kate& Rowlands, Victoria J.& Short, Darryl& Metcalf, Daniel G.& Bowler, Philip G.. 2016. Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing. BioMed Research International،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1098830
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Parsons, David…[et al.]. Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing. BioMed Research International No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1098830
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Parsons, David& Meredith, Kate& Rowlands, Victoria J.& Short, Darryl& Metcalf, Daniel G.& Bowler, Philip G.. Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1098830
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1098830
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر