Plasma Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Cardiovascular Events in Patients with Chronic Kidney Disease
المؤلفون المشاركون
Hasegawa, Midori
Ishii, Junichi
Kitagawa, Fumihiko
Takahashi, Hiroshi
Sugiyama, Kazuhiro
Tada, Masashi
Kanayama, Kyoko
Takahashi, Kazuo
Hayashi, Hiroki
Koide, Shigehisa
Nakai, Shigeru
Ozaki, Yukio
Yuzawa, Yukio
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Our aim was to assess plasma neutrophil gelatinase-associated lipocalin (NGAL) as a predictor of cardiovascular (CV) events in patients with chronic kidney disease (CKD) and no history of CV events.
Methods.
This was a prospective observational cohort study of 252 patients with predialysis CKD.
CV events were defined as CV death, acute coronary syndrome, and hospitalization for worsening heart failure, stroke, and aortic dissection.
Results.
During a median follow-up period of 63 months, 36 CV events occurred.
On Cox stepwise multivariate analysis, plasma NGAL and B-type natriuretic peptide (BNP) were significant predictors of CV events.
Kaplan-Meier incidence rates of CV event-free survival at 5 years were 96.6%, 92.9%, 85.9%, and 61.3%, respectively, among quartiles of plasma NGAL ( P < 0 .
0001 ).
The C-index for the receiver-operating characteristic curves for CV events was greater when plasma NGAL was added to an established risk model (0.801, 95% CI 0.717–0.885), compared to the model without plasma NGAL (0.746, 95% CI 0.653–0.840, P = 0.0 21 ).
Conclusion.
Elevated plasma NGAL could predict future CV events in CKD patients with no history of CV events and add incremental value to the established risk model.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hasegawa, Midori& Ishii, Junichi& Kitagawa, Fumihiko& Takahashi, Hiroshi& Sugiyama, Kazuhiro& Tada, Masashi…[et al.]. 2016. Plasma Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Cardiovascular Events in Patients with Chronic Kidney Disease. BioMed Research International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099137
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hasegawa, Midori…[et al.]. Plasma Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Cardiovascular Events in Patients with Chronic Kidney Disease. BioMed Research International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1099137
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hasegawa, Midori& Ishii, Junichi& Kitagawa, Fumihiko& Takahashi, Hiroshi& Sugiyama, Kazuhiro& Tada, Masashi…[et al.]. Plasma Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Cardiovascular Events in Patients with Chronic Kidney Disease. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1099137
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099137
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر