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Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children
المؤلفون المشاركون
Wami, Welcome M.
Midzi, Nicholas
Gwisai, Reggis
Mduluza, Takafira
Woolhouse, Mark E. J.
Mutapi, Francisca
Nausch, Norman
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-18
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Schistosomiasis is a major public health problem in Africa.
However, it is only recently that its burden has become recognised as a significant component impacting on the health and development of preschool-aged children.
A longitudinal study was conducted in Zimbabwean children to determine the effect of single praziquantel treatment on Schistosoma haematobium-related morbidity markers: microhaematuria, proteinuria, and albuminuria.
Changes in these indicators were compared in 1–5 years versus 6–10 years age groups to determine if treatment outcomes differed by age.
Praziquantel was efficacious at reducing infection 12 weeks after treatment: cure rate = 94.6% (95% CI: 87.9–97.7%).
Infection rates remained lower at 12 months after treatment compared to baseline in both age groups.
Among treated children, the odds of morbidity at 12 weeks were significantly lower compared to baseline for proteinuria: odds ratio (OR) = 0.54 (95% CI: 0.31–0.95) and albuminuria: OR = 0.05 (95% CI: 0.02–0.14).
Microhaematuria significantly reduced 12 months after treatment, and the effect of treatment did not differ by age group: OR = 0.97 (95% CI: 0.50–1.87).
In conclusion, praziquantel treatment has health benefits in preschool-aged children exposed to S.
haematobium and its efficacy on infection and morbidity is not age-dependent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wami, Welcome M.& Nausch, Norman& Midzi, Nicholas& Gwisai, Reggis& Mduluza, Takafira& Woolhouse, Mark E. J.…[et al.]. 2016. Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children. BioMed Research International،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1099244
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wami, Welcome M.…[et al.]. Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children. BioMed Research International No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1099244
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wami, Welcome M.& Nausch, Norman& Midzi, Nicholas& Gwisai, Reggis& Mduluza, Takafira& Woolhouse, Mark E. J.…[et al.]. Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1099244
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099244
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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