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Clinical Manifestations and Myositis-Specific Autoantibodies Associated with Physical Dysfunction after Treatment in Polymyositis and Dermatomyositis: An Observational Study of Physical Dysfunction with Myositis in Japan
المؤلفون المشاركون
Kuwana, Masataka
Katsumata, Yasuhiro
Kataoka, Sayuri
Gono, Takahisa
Yamanaka, Hisashi
Kawaguchi, Yasushi
Kaneko, Hirotaka
Kawasumi, Hidenaga
Hanaoka, Masanori
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-26
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
The physical function of PM/DM patients after remission induction therapy remains unknown adequately.
The aim of our study was to evaluate the present status of physical dysfunction and to clarify the clinical manifestations and myositis-specific autoantibodies (MSAs) associated with physical dysfunction after treatment in PM/DM.
Methods.
We obtained clinical data including the age at disease onset, gender, disease duration, laboratory data prior to initial treatment, and the specific treatment administered.
We evaluated disease activity and physical dysfunction after treatment using the core set provided by the International Myositis Assessment and Clinical Studies Group.
Results.
57% of the 77 enrolled patients with PM/DM had troubles in daily living after treatment.
At the enrolment, disease activity evaluated by physicians was only revealed in 20% of patients.
In a multivariate analysis, the age at disease onset, female gender, and CK levels before treatment were significantly associated with the severity of physical dysfunction after treatment.
Anti-SRP positivity was associated with more severe physical dysfunction after treatment than anti-ARS or anti-MDA5.
Conclusions.
Half of the PM/DM patients showed physical dysfunction after treatment.
Age at disease onset, gender, CK level before treatment, and anti-SRP were significant predictors associated with physical dysfunction after treatment in PM/DM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kawasumi, Hidenaga& Gono, Takahisa& Kawaguchi, Yasushi& Kuwana, Masataka& Kaneko, Hirotaka& Katsumata, Yasuhiro…[et al.]. 2016. Clinical Manifestations and Myositis-Specific Autoantibodies Associated with Physical Dysfunction after Treatment in Polymyositis and Dermatomyositis: An Observational Study of Physical Dysfunction with Myositis in Japan. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1099245
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kawasumi, Hidenaga…[et al.]. Clinical Manifestations and Myositis-Specific Autoantibodies Associated with Physical Dysfunction after Treatment in Polymyositis and Dermatomyositis: An Observational Study of Physical Dysfunction with Myositis in Japan. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1099245
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kawasumi, Hidenaga& Gono, Takahisa& Kawaguchi, Yasushi& Kuwana, Masataka& Kaneko, Hirotaka& Katsumata, Yasuhiro…[et al.]. Clinical Manifestations and Myositis-Specific Autoantibodies Associated with Physical Dysfunction after Treatment in Polymyositis and Dermatomyositis: An Observational Study of Physical Dysfunction with Myositis in Japan. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1099245
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099245
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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