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Characterization of Enhancing MS Lesions by Dynamic Texture Parameter Analysis of Dynamic Susceptibility Perfusion Imaging
المؤلفون المشاركون
Verma, Rajeev K.
Slotboom, Johannes
Locher, Cäcilia
Heldner, Mirjam R.
Weisstanner, Christian
Abela, Eugenio
Kellner-Weldon, Frauke
Zbinden, Martin
Kamm, Christian P.
Wiest, Roland
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-13
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
The purpose of this study was to investigate statistical differences with MR perfusion imaging features that reflect the dynamics of Gadolinium-uptake in MS lesions using dynamic texture parameter analysis (DTPA).
Methods.
We investigated 51 MS lesions (25 enhancing, 26 nonenhancing lesions) of 12 patients.
Enhancing lesions ( n = 25 ) were prestratified into enhancing lesions with increased permeability (EL+; n = 11 ) and enhancing lesions with subtle permeability (EL−; n = 14 ).
Histogram-based feature maps were computed from the raw DSC-image time series and the corresponding texture parameters were analyzed during the inflow, outflow, and reperfusion time intervals.
Results.
Significant differences ( p < 0.05 ) were found between EL+ and EL− and between EL+ and nonenhancing inactive lesions (NEL).
Main effects between EL+ versus EL− and EL+ versus NEL were observed during reperfusion (mainly in mean and standard deviation (SD): EL+ versus EL− and EL+ versus NEL), while EL− and NEL differed only in their SD during outflow.
Conclusion.
DTPA allows grading enhancing MS lesions according to their perfusion characteristics.
Texture parameters of EL− were similar to NEL, while EL+ differed significantly from EL− and NEL.
Dynamic texture analysis may thus be further investigated as noninvasive endogenous marker of lesion formation and restoration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Verma, Rajeev K.& Slotboom, Johannes& Locher, Cäcilia& Heldner, Mirjam R.& Weisstanner, Christian& Abela, Eugenio…[et al.]. 2016. Characterization of Enhancing MS Lesions by Dynamic Texture Parameter Analysis of Dynamic Susceptibility Perfusion Imaging. BioMed Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1099324
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Verma, Rajeev K.…[et al.]. Characterization of Enhancing MS Lesions by Dynamic Texture Parameter Analysis of Dynamic Susceptibility Perfusion Imaging. BioMed Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1099324
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Verma, Rajeev K.& Slotboom, Johannes& Locher, Cäcilia& Heldner, Mirjam R.& Weisstanner, Christian& Abela, Eugenio…[et al.]. Characterization of Enhancing MS Lesions by Dynamic Texture Parameter Analysis of Dynamic Susceptibility Perfusion Imaging. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1099324
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099324
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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