Immunocompromised Children with Severe Adenoviral Respiratory Infection
المؤلفون المشاركون
Tylka, Joanna C.
McCrory, Michael C.
Gertz, Shira J.
Custer, Jason W.
Spaeder, Michael C.
المصدر
Critical Care Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-08
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To investigate the impact of severe respiratory adenoviral infection on morbidity and case fatality in immunocompromised children.
Methods.
Combined retrospective-prospective cohort study of patients admitted to the intensive care unit (ICU) in four children’s hospitals with severe adenoviral respiratory infection and an immunocompromised state between August 2009 and October 2013.
We performed a secondary case control analysis, matching our cohort 1 : 1 by age and severity of illness score with immunocompetent patients also with severe respiratory adenoviral infection.
Results.
Nineteen immunocompromised patients were included in our analysis.
Eleven patients (58%) did not survive to hospital discharge.
Case fatality was associated with cause of immunocompromised state ( p = 0.015 ), multiple organ dysfunction syndrome ( p = 0.001 ), requirement of renal replacement therapy ( p = 0.01 ), ICU admission severity of illness score ( p = 0.011 ), and treatment with cidofovir ( p = 0.005 ).
Immunocompromised patients were more likely than matched controls to have multiple organ dysfunction syndrome ( p = 0.01 ), require renal replacement therapy ( p = 0.02 ), and not survive to hospital discharge ( p = 0.004 ).
One year after infection, 43% of immunocompromised survivors required chronic mechanical ventilator support.
Conclusions.
There is substantial case fatality as well as short- and long-term morbidity associated with severe adenoviral respiratory infection in immunocompromised children.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tylka, Joanna C.& McCrory, Michael C.& Gertz, Shira J.& Custer, Jason W.& Spaeder, Michael C.. 2016. Immunocompromised Children with Severe Adenoviral Respiratory Infection. Critical Care Research and Practice،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1099550
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tylka, Joanna C.…[et al.]. Immunocompromised Children with Severe Adenoviral Respiratory Infection. Critical Care Research and Practice No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1099550
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tylka, Joanna C.& McCrory, Michael C.& Gertz, Shira J.& Custer, Jason W.& Spaeder, Michael C.. Immunocompromised Children with Severe Adenoviral Respiratory Infection. Critical Care Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1099550
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099550
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر