Comparison of One versus Two Fecal Immunochemical Tests in the Detection of Colorectal Neoplasia in a Population-Based Colorectal Cancer Screening Program
المؤلفون المشاركون
Enns, Robert
Gentile, Laura
Gondara, Lovedeep
McGahan, Colleen E.
Telford, Jennifer
Moosavi, Sarvenaz
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-01
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To determine the positive predictive value (PPV) of two versus one abnormal FIT in the detection of colorectal neoplasia in a Canadian population.
Methods.
Three communities enrolled in a colorectal cancer (CRC) screening pilot program from 01/2009 to 04/2013 using 2 FITs.
Data collected included demographics, colonoscopy, pathology, and FIT results.
Participants completed both FITs and had one positive FIT and colonoscopy.
PPV of one versus two abnormal FITs was calculated using a weighted-generalized score statistic.
A two-sided 5% significance level was used.
Results.
1576 of 17,031 average-risk participants, 50–75 years old, had a positive FIT.
Colonoscopy revealed 58 (3.7%) cancers, 419 (31.6%) high-risk polyps, and 374 (23.7%) low-risk polyps as the most significant lesion.
PPV of one versus two positive FITs for cancer, high-risk polyps, and any neoplasia were 1% versus 8%, 20% versus 40%, and 48% versus 67%, respectively (p value < 0.0001).
When the first FIT was negative, the second positive FIT detected 7 CRCs and 98 high-risk polyps.
Conclusions.
PPV of two positive FITs is superior to one positive FIT for CRC and high-risk polyps.
The added value of the second FIT was 12% of total CRCs and 23% of total high-risk polyps.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Moosavi, Sarvenaz& Enns, Robert& Gentile, Laura& Gondara, Lovedeep& McGahan, Colleen E.& Telford, Jennifer. 2016. Comparison of One versus Two Fecal Immunochemical Tests in the Detection of Colorectal Neoplasia in a Population-Based Colorectal Cancer Screening Program. Canadian Journal of Gastroenterology and Hepatology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1099895
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Moosavi, Sarvenaz…[et al.]. Comparison of One versus Two Fecal Immunochemical Tests in the Detection of Colorectal Neoplasia in a Population-Based Colorectal Cancer Screening Program. Canadian Journal of Gastroenterology and Hepatology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1099895
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Moosavi, Sarvenaz& Enns, Robert& Gentile, Laura& Gondara, Lovedeep& McGahan, Colleen E.& Telford, Jennifer. Comparison of One versus Two Fecal Immunochemical Tests in the Detection of Colorectal Neoplasia in a Population-Based Colorectal Cancer Screening Program. Canadian Journal of Gastroenterology and Hepatology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1099895
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1099895
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر