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Loperamide Induced Life Threatening Ventricular Arrhythmia
المؤلفون المشاركون
Upadhyay, Ankit
Bodar, Vijaykumar
Malekzadegan, Mohammad
Singh, Sharanjit
Frumkin, William
Mangla, Aditya
Doshi, Kaushik
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-28
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors.
It is gaining popularity among drug abusers as opioid substitute.
We report a case of a 46-year-old male that was presented after cardiac arrest.
After ruling out ischemia, cardiomyopathy, pulmonary embolism, central nervous system pathology, sepsis, and other drug toxicity, we found out that patient was using around 100 mg of Loperamide to control his chronic diarrhea presumably because of irritable bowel syndrome for last five years and consumed up to 200 mg of Loperamide daily for last two days before the cardiac arrest.
We hypothesize that the patient’s QTc prolongation and subsequent cardiac arrest are due to Loperamide toxicity.
Patient experienced gradual resolution of tachyarrhythmia and gradual decrease in QTc interval during hospitalization which supports the evidence of causal relationship between Loperamide overdose and potentially fatal arrhythmias.
It also provided the clue that patient may have congenital long QT syndrome which was unmasked by Loperamide causing ventricular arrhythmias.
This case adds one more pearl in the literature to support that Loperamide overdose related cardiac toxicity does exist and it raises concerns over Loperamide abuse in the community.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Upadhyay, Ankit& Bodar, Vijaykumar& Malekzadegan, Mohammad& Singh, Sharanjit& Frumkin, William& Mangla, Aditya…[et al.]. 2016. Loperamide Induced Life Threatening Ventricular Arrhythmia. Case Reports in Cardiology،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100345
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Upadhyay, Ankit…[et al.]. Loperamide Induced Life Threatening Ventricular Arrhythmia. Case Reports in Cardiology No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100345
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Upadhyay, Ankit& Bodar, Vijaykumar& Malekzadegan, Mohammad& Singh, Sharanjit& Frumkin, William& Mangla, Aditya…[et al.]. Loperamide Induced Life Threatening Ventricular Arrhythmia. Case Reports in Cardiology. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100345
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1100345
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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