Hip Replacement Surgery in 14-Year-Old Girl with Factor V Deficiency: Haemostatic Treatment and Thromboprophylaxis
المؤلفون المشاركون
Mingot-Castellano, María Eva
Pérez-Núñez, Josefina
Baeza-Montañez, Lourdes
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-30
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Factor V (FV) is a pivotal coagulation factor present in plasma and platelets.
It plays an essential role in secondary haemostasis acting as a cofactor in the prothrombinase complex, catalysing the conversion of prothrombin to thrombin.
There is little evidence on the management of mayor orthopaedic surgery in paediatric or adolescents subjects with this coagulopathy and almost no information about thromboprophylaxis in these situations.
We report a case of a hip replacement in a 14-year-old girl with moderate FV deficiency (0.07 IU mL−1).
As haemostatic replacement, inactivated fresh frozen plasma (FFP) was transfused at doses of 600 mL (15 mL kg−1, 45 kg weight) 2 hours before surgery and then sequential FFP infusions of 250 mL (7 mL kg−1) every 12 hours for 7 days.
Plasma factor VIII, von Willebrand factor antigen, and von Willebrand ristocetin cofactor were monitored to avoid supranormal levels.
Since the patient was sexually mature (Marshall and Tanner stage 5) with the hormone replacement therapy, she was immobilized and the surgery was considered as a high thrombotic risk.
Thus, low molecular weight heparin was administered at doses of intermediate risk (Enoxaparin 20 mg daily, by weight) after finishing the daily infusion of plasma: 24 hours and during the 7 days after intervention.
No tranexamic acid was used.
No haemorrhagic or thrombotic adverse event was described.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mingot-Castellano, María Eva& Pérez-Núñez, Josefina& Baeza-Montañez, Lourdes. 2016. Hip Replacement Surgery in 14-Year-Old Girl with Factor V Deficiency: Haemostatic Treatment and Thromboprophylaxis. Case Reports in Hematology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100859
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mingot-Castellano, María Eva…[et al.]. Hip Replacement Surgery in 14-Year-Old Girl with Factor V Deficiency: Haemostatic Treatment and Thromboprophylaxis. Case Reports in Hematology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100859
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mingot-Castellano, María Eva& Pérez-Núñez, Josefina& Baeza-Montañez, Lourdes. Hip Replacement Surgery in 14-Year-Old Girl with Factor V Deficiency: Haemostatic Treatment and Thromboprophylaxis. Case Reports in Hematology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100859
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1100859
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر