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Autoimmune Lymphoproliferative Syndrome: A Rare Cause of Disappearing HDL Syndrome
المؤلفون المشاركون
Sriram, Swetha
Rodriguez, Vilmarie
Kumar, Seema
Joshi, Avni Y.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-08
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
The term disappearing HDL syndrome refers to development of severe high density lipoprotein cholesterol (HDL-C) deficiency in noncritically ill patients with previously normal HDL-C and triglyceride levels.
Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of the immune system due to an inability to regulate lymphocyte homeostasis resulting in lymphadenopathy and hepatosplenomegaly.
We describe a 17-year-old boy who was evaluated in the lipid clinic for history of undetectable or low HDL-C and low density lipoprotein cholesterol (LDL-C) levels.
Past medical history was significant for ALPS IA diagnosed at 10 years of age when he presented with bilateral cervical adenopathy.
He was known to have a missense mutation in one allele of the FAS protein extracellular domain consistent with ALPS type 1A.
HDL-C and LDL-C levels had been undetectable on multiple occasions, though lipids had not been measured prior to the diagnosis of ALPS.
He had been receiving sirolimus for immunosuppression.
The HDL-C and LDL-C levels correlated with disease activity and improved to normal levels during times when the activity of ALPS was controlled.
This case highlights the importance of considering ALPS as a cause of low HDL-C and LDL-C levels in a child with evidence of lymphoproliferation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sriram, Swetha& Joshi, Avni Y.& Rodriguez, Vilmarie& Kumar, Seema. 2016. Autoimmune Lymphoproliferative Syndrome: A Rare Cause of Disappearing HDL Syndrome. Case Reports in Immunology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100928
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sriram, Swetha…[et al.]. Autoimmune Lymphoproliferative Syndrome: A Rare Cause of Disappearing HDL Syndrome. Case Reports in Immunology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1100928
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sriram, Swetha& Joshi, Avni Y.& Rodriguez, Vilmarie& Kumar, Seema. Autoimmune Lymphoproliferative Syndrome: A Rare Cause of Disappearing HDL Syndrome. Case Reports in Immunology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1100928
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1100928
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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