Q Fever Risk in Patients Treated with Chronic Antitumor Necrosis Factor-Alpha Therapy

الملخص EN

Q fever is a zoonotic bacterial disease caused by Coxiella burnetii.

Tumor necrosis factor-alpha (TNF-α) plays a pivotal role in the defense against infection with this Gram-negative coccobacillus.

Theoretically, patients who are treated with anti-TNF-α medications are at risk for developing chronic Q fever.

We present two patients who developed Q fever while being treated with anti-TNF-α agents and discuss the significance of timely diagnosis of C.

burnetii infection in these patients.