Spinal Cord Infarction in a Patient with Hereditary Spherocytosis: A Case Report and Discussion
المؤلفون المشاركون
Pendlebury, William
Waheed, Waqar
Varigonda, Anjali L.
Holmes, Chris E.
Trevino, Christopher
Borden, Neil M.
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The etiology of spinal cord infarcts (SCIs), besides being related to aortic perioperative events, in large subset of SCIs, remains cryptogenic.
We present a first case of SCI in a patient with hereditary spherocytosis and discuss the potential pathophysiologic considerations for vascular compromise.
A 43-year-old woman with a history of hereditary spherocytosis, post splenectomy status, presented with chest, back, and shoulder pain with subsequent myelopathic picture; SCI extending from C4-T2 was confirmed by MRI.
Despite aggressive treatment her stroke progressed leading to her demise.
Her autopsy confirmed the SCI and revealed some incidental findings, but the cause of SCI remained unidentified.
Exclusion of the known etiologies of SCI by extensive negative workup including autopsy evaluation suggested that SCI in our case was related to her history of hereditary spherocytosis.
Both venous and arterial adverse vascular events, at a higher rate, have been associated in patients with hereditary spherocytosis who had their spleens removed compared to nonsplenectomized patients.
Postsplenectomy increases in the platelet, red blood cell count, leukocyte count, and cholesterol concentrations are postulated to contribute to increased thrombotic risk.
Additional prothrombotic factors include continuous platelet activation and adhesion as well as abnormalities of the red blood cell membrane.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Waheed, Waqar& Varigonda, Anjali L.& Holmes, Chris E.& Trevino, Christopher& Borden, Neil M.& Pendlebury, William. 2016. Spinal Cord Infarction in a Patient with Hereditary Spherocytosis: A Case Report and Discussion. Case Reports in Neurological Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1101312
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Waheed, Waqar…[et al.]. Spinal Cord Infarction in a Patient with Hereditary Spherocytosis: A Case Report and Discussion. Case Reports in Neurological Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1101312
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Waheed, Waqar& Varigonda, Anjali L.& Holmes, Chris E.& Trevino, Christopher& Borden, Neil M.& Pendlebury, William. Spinal Cord Infarction in a Patient with Hereditary Spherocytosis: A Case Report and Discussion. Case Reports in Neurological Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1101312
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1101312
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر