Nonobstructive Acute Renal Failure with a Large Solitary Fibroid

الملخص EN

A 38-year-old African American woman presenting with acute abdominal pain and nonobstructive renal failure was found to have an enlarged fibroid uterus.

A differential for sepsis was considered.

Lab evaluation revealed an elevated creatinine and myoglobin level at 3.9 mg/dL and 2140 ng/mL, respectively.

Ongoing hemodynamic instability mandated surgery for acute abdomen.

A 25 cm fibroid uterus was extirpated through a total abdominal hysterectomy.

Immediate improvement of acute nephropathy mirrored the postoperative decline in serum myoglobin levels.

Myoglobinemia from a massive degenerating fibroid is associated with nonobstructive acute renal failure.