Primary Diffuse Large B-Cell Lymphoma of the Liver in a Patient with Sjogren Syndrome
المؤلفون المشاركون
Gorodetskiy, Vadim
Klapper, Wolfram
Probatova, Natalya
Vasilyev, Vladimir
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Sjögren’s syndrome (SS) has the highest incidence of malignant lymphoproliferative disorders transformation among autoimmune diseases.
We present a case of extranodal high grade lymphoma of the liver in a 52-year-old patient with long history of SS.
Lymphoma manifested with sharp significant pain in the right hypochondrium, weakness, and profuse night sweats.
Contrast-enhanced computed tomography scan (CT-scan) of the abdomen revealed multiple low density foci with homogeneous structure and clear contours in both lobes of the liver.
Histologically, proliferation of medium sized lymphoma cells with round-oval and slightly irregular nuclei with fine chromatin was shown.
Immunohistochemical and molecular features of the tumors allowed diagnosis of diffuse large B-cell lymphoma (DLBCL).
To exclude secondary liver lesion by non-Hodgkin lymphoma, chest and small pelvis CT-scan, endoscopy of upper and lower gastrointestinal tract and study of bone marrow were performed.
After 8 cycles of R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone), the complete remission was achieved, which persists after 45 months of follow-up.
Primary hepatic lymphomas are extremely rare, and previously only low-grade hepatic lymphomas have been described in SS.
To our knowledge, the patient described here represents the first reported case of DLBCL with primary liver involvement in SS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gorodetskiy, Vadim& Klapper, Wolfram& Probatova, Natalya& Vasilyev, Vladimir. 2016. Primary Diffuse Large B-Cell Lymphoma of the Liver in a Patient with Sjogren Syndrome. Case Reports in Oncological Medicine،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101648
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gorodetskiy, Vadim…[et al.]. Primary Diffuse Large B-Cell Lymphoma of the Liver in a Patient with Sjogren Syndrome. Case Reports in Oncological Medicine No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1101648
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gorodetskiy, Vadim& Klapper, Wolfram& Probatova, Natalya& Vasilyev, Vladimir. Primary Diffuse Large B-Cell Lymphoma of the Liver in a Patient with Sjogren Syndrome. Case Reports in Oncological Medicine. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1101648
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1101648
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر