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The Modification Effect of Influenza Vaccine on Prognostic Indicators for Cardiovascular Events after Acute Coronary Syndrome: Observations from an Influenza Vaccination Trial
المؤلفون المشاركون
Sribhutorn, Apirak
Phrommintikul, Arintaya
Wongcharoen, Wanwarang
Chaikledkaew, Usa
Eakanunkul, Suntara
Sukonthasarn, Apichard
المصدر
Cardiology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-20
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
The prognosis of acute coronary syndrome (ACS) patients has been improved with several treatments such as antithrombotics, beta-blockers, and angiotensin-converting enzyme inhibitors (ACEI) as well as coronary revascularization.
Influenza vaccination has been shown to reduce adverse outcomes in ACS, but no information exists regarding the interaction of other treatments.
Methods.
This study included 439 ACS patients from Phrommintikul et al.
A single dose of inactivated influenza vaccine was given by intramuscular injection in the vaccination group.
The cardiovascular outcomes were described as major cardiovascular events (MACEs) which included mortality, hospitalization due to ACS, and hospitalization due to heart failure (HF).
The stratified and multivariable Cox’s regression analysis was performed.
Results.
The stratified Cox’s analysis by influenza vaccination for each cardiovascular outcome and discrimination of hazard ratios showed that beta-blockers had an interaction with influenza vaccination.
Moreover, the multivariable hazard ratios disclosed that influenza vaccine is associated with a significant reduction of hospitalization due to HF in patients who received beta-blockers (HR = 0.05, 95% CI = 0.004–0.71, P = 0.027 ), after being adjusted for prognostic indicators (sex, dyslipidemia, serum creatinine, and left ventricular ejection fraction).
Conclusions.
The influenza vaccine was shown to significantly modify the effect of beta-blockers in ACS patients and to reduce the hospitalization due to HF.
However, further study of a larger population and benefits to HF patients should be investigated.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sribhutorn, Apirak& Phrommintikul, Arintaya& Wongcharoen, Wanwarang& Chaikledkaew, Usa& Eakanunkul, Suntara& Sukonthasarn, Apichard. 2016. The Modification Effect of Influenza Vaccine on Prognostic Indicators for Cardiovascular Events after Acute Coronary Syndrome: Observations from an Influenza Vaccination Trial. Cardiology Research and Practice،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103284
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sribhutorn, Apirak…[et al.]. The Modification Effect of Influenza Vaccine on Prognostic Indicators for Cardiovascular Events after Acute Coronary Syndrome: Observations from an Influenza Vaccination Trial. Cardiology Research and Practice No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103284
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sribhutorn, Apirak& Phrommintikul, Arintaya& Wongcharoen, Wanwarang& Chaikledkaew, Usa& Eakanunkul, Suntara& Sukonthasarn, Apichard. The Modification Effect of Influenza Vaccine on Prognostic Indicators for Cardiovascular Events after Acute Coronary Syndrome: Observations from an Influenza Vaccination Trial. Cardiology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103284
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103284
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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