Can the Neutrophil to Lymphocyte Ratio Be Used to Determine Gastric Cancer Treatment Outcomes? A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Song, Yong-xi
Huang, Xuan-zhang
Gao, Peng
Sun, Jing-xu
Chen, Xiao-wan
Yang, Yu-chong
Wang, Zhen-ning
Zhao, Junhua
Ma, Bin
Gao, X.-H.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-26
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The prognostic role of neutrophil to lymphocyte ratio (NLR) in gastric cancer remains controversial.
We aimed to quantify the prognostic role of peripheral blood NLR in gastric cancer.
A literature search was conducted in PubMed, EMBASE, and Cochrane databases.
The results for overall survival (OS) and progression-free survival (PFS)/disease-free survival (DFS) are expressed as hazard ratios (HRs) with 95% confidence intervals (CIs).
19 studies with 5431 patients were eligible for final analysis.
Elevated NLRs were associated with a significantly poor outcome for OS (HR = 1.98; 95% CI: 1.75–2.24, p<0.001) and PFS (HR = 1.58; 95% CI: 1.32–1.88, p<0.001) compared with patients who had normal NLRs.
The NLR was higher for patients with late-stage compared with early-stage gastric cancer (OR = 2.76; 95% CI: 1.36–5.61, p=0.005).
NLR lost its predictive role for patients with stage IV gastric cancer who received palliative surgery (HR = 1.73; 95% CI: 0.85–3.54, p=0.13).
Our results also indicated that prognoses might be influenced by the NLR cutoff values.
In conclusion, elevated pretreatment NLRs are associated with poor outcome for patients with gastric cancer.
The ability to use the NLR to evaluate the status of patients may be used in the future for personalized cancer care.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Jing-xu& Chen, Xiao-wan& Gao, Peng& Song, Yong-xi& Huang, Xuan-zhang& Yang, Yu-chong…[et al.]. 2016. Can the Neutrophil to Lymphocyte Ratio Be Used to Determine Gastric Cancer Treatment Outcomes? A Systematic Review and Meta-Analysis. Disease Markers،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1103774
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Jing-xu…[et al.]. Can the Neutrophil to Lymphocyte Ratio Be Used to Determine Gastric Cancer Treatment Outcomes? A Systematic Review and Meta-Analysis. Disease Markers No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1103774
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Jing-xu& Chen, Xiao-wan& Gao, Peng& Song, Yong-xi& Huang, Xuan-zhang& Yang, Yu-chong…[et al.]. Can the Neutrophil to Lymphocyte Ratio Be Used to Determine Gastric Cancer Treatment Outcomes? A Systematic Review and Meta-Analysis. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1103774
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103774
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر