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Recurrence of Dysplastic Nevi Is Strongly Associated with Extension of the Lesions to the Lateral Margins and into the Deep Margins through the Hair Follicles in the Original Shave Removal Specimens
المؤلف
المصدر
Dermatology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-28
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Melanocytic nevi, including dysplastic or atypical nevi (DN), can recur or persist following shave removal procedures, and recurrence may resemble melanoma, both clinically and histologically (pseudomelanoma).
Recurrence may originate from proliferation of the remaining neoplastic melanocytes following incomplete removal.
The present study determines the rate and etiology of this event.
A cross-sectional analysis of 110 excision specimens showing histological recurrence was performed, and these specimens were compared to the slides of the original shave specimens showing mildly atypical DN.
In the second portion of the study, a retrospective review of 167 cases with biopsy-proven mildly atypical DN which were followed up for at least two years was conducted to determine the rate of recurrence/persistence.
When followed up for two years, DN, with positive shave margins, defined by extension or very close extension (≤0.2 mm) of the lesions to the lateral margins and into the deep margins through the hair follicles in the shave removal specimens, have a higher probability of recurrence than DN with negative (or clear) margins (odds ratio (OR) = 158; 95% confidence interval (CI) = 36.62–683; P<0.001).
The overall rate of histologically confirmed recurrence/persistence was approximately 10%.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Maghari, Amin. 2016. Recurrence of Dysplastic Nevi Is Strongly Associated with Extension of the Lesions to the Lateral Margins and into the Deep Margins through the Hair Follicles in the Original Shave Removal Specimens. Dermatology Research and Practice،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1103849
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Maghari, Amin. Recurrence of Dysplastic Nevi Is Strongly Associated with Extension of the Lesions to the Lateral Margins and into the Deep Margins through the Hair Follicles in the Original Shave Removal Specimens. Dermatology Research and Practice No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1103849
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Maghari, Amin. Recurrence of Dysplastic Nevi Is Strongly Associated with Extension of the Lesions to the Lateral Margins and into the Deep Margins through the Hair Follicles in the Original Shave Removal Specimens. Dermatology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1103849
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103849
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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