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Antibacterial and Antibiofilm Activity of Methanolic Plant Extracts against Nosocomial Microorganisms
المؤلفون المشاركون
Sánchez, Eduardo
Rivas Morales, Catalina
Castillo, Sandra
Leos-Rivas, Catalina
García-Becerra, Ledy
Ortiz Martínez, David Mizael
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Biofilm is a complex microbial community highly resistant to antimicrobials.
The formation of biofilms in biotic and abiotic surfaces is associated with high rates of morbidity and mortality in hospitalized patients.
New alternatives for controlling infections have been proposed focusing on the therapeutic properties of medicinal plants and their antimicrobial effects.
In the present study the antimicrobial and antibiofilm activities of 8 methanolic plant extracts were evaluated against clinical isolated microorganisms.
Preliminary screening by diffusion well assay showed the antimicrobial activity of Prosopis laevigata, Opuntia ficus-indica, and Gutierrezia microcephala.
The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined ranging from 0.7 to >15 mg/mL.
The specific biofilm formation index (SBF) was evaluated before and after the addition of plant extracts (MBC × 0.75).
Opuntia ficus-indica caused the major reduction on SBF in dose-dependent manner.
Cytotoxic activity of plant extracts was determined using brine shrimp lethality test (Artemia salina L.).
Lethal Dose concentration (LD50 values) of the plant extracts was calculated.
LD50 values for P.
laevigata and G.
microcephala were 141.6 and 323.3 µg/mL, respectively, while O.
ficus-indica showed a slight lethality with 939.2 µg/mL.
Phytochemical analyses reveal the presence of flavonoids, tannins, and coumarines.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sánchez, Eduardo& Rivas Morales, Catalina& Castillo, Sandra& Leos-Rivas, Catalina& García-Becerra, Ledy& Ortiz Martínez, David Mizael. 2016. Antibacterial and Antibiofilm Activity of Methanolic Plant Extracts against Nosocomial Microorganisms. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103913
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sánchez, Eduardo…[et al.]. Antibacterial and Antibiofilm Activity of Methanolic Plant Extracts against Nosocomial Microorganisms. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103913
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sánchez, Eduardo& Rivas Morales, Catalina& Castillo, Sandra& Leos-Rivas, Catalina& García-Becerra, Ledy& Ortiz Martínez, David Mizael. Antibacterial and Antibiofilm Activity of Methanolic Plant Extracts against Nosocomial Microorganisms. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103913
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103913
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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