Chamaecyparis obtusa Suppresses Virulence Genes in Streptococcus mutans
المؤلفون المشاركون
You, Yong-Ouk
Kim, Young-Hoi
Kim, Eun-Hee
Hoe, Jin-Hee
Ra, Ji-Young
Lee, Young-Rae
Kang, Sun-Young
Park, Bok-Im
An, So-youn
Choi, Na-Young
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Chamaecyparis obtusa (C.
obtusa) is known to have antimicrobial effects and has been used as a medicinal plant and in forest bathing.
This study aimed to evaluate the anticariogenic activity of essential oil of C.
obtusa on Streptococcus mutans, which is one of the most important bacterial causes of dental caries and dental biofilm formation.
Essential oil from C.
obtusa was extracted, and its effect on bacterial growth, acid production, and biofilm formation was evaluated.
C.
obtusa essential oil exhibited concentration-dependent inhibition of bacterial growth over 0.025 mg/mL, with 99% inhibition at a concentration of 0.2 mg/mL.
The bacterial biofilm formation and acid production were also significantly inhibited at the concentration greater than 0.025 mg/mL.
The result of LIVE/DEAD® BacLight™ Bacterial Viability Kit showed a concentration-dependent bactericidal effect on S.
mutans and almost all bacteria were dead over 0.8 mg/mL.
Real-time PCR analysis showed that gene expression of some virulence factors such as brpA, gbpB, gtfC, and gtfD was also inhibited.
In GC and GC-MS analysis, the major components were found to be α-terpinene (40.60%), bornyl acetate (12.45%), α-pinene (11.38%), β-pinene (7.22%), β-phellandrene (3.45%), and α-terpinolene (3.40%).
These results show that C.
obtusa essential oil has anticariogenic effect on S.
mutans.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Eun-Hee& Kang, Sun-Young& Park, Bok-Im& Kim, Young-Hoi& Lee, Young-Rae& Hoe, Jin-Hee…[et al.]. 2016. Chamaecyparis obtusa Suppresses Virulence Genes in Streptococcus mutans. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103982
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Eun-Hee…[et al.]. Chamaecyparis obtusa Suppresses Virulence Genes in Streptococcus mutans. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103982
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Eun-Hee& Kang, Sun-Young& Park, Bok-Im& Kim, Young-Hoi& Lee, Young-Rae& Hoe, Jin-Hee…[et al.]. Chamaecyparis obtusa Suppresses Virulence Genes in Streptococcus mutans. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103982
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103982
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر