Radix Astragali-Based Chinese Herbal Medicine for Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Deng, Bo
Jia, Li-qun
Cheng, Zhiqiang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-04
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Background.
Treatment of chemotherapy-induced peripheral neuropathy (CIPN) remains a big challenge for oncologists.
The aim of this study is to evaluate the effects of Radix Astragali- (RA-) based Chinese herbal medicine in the prevention and treatment of oxaliplatin-induced peripheral neuropathy, including the incidence and grading of neurotoxicity, effective percentage, and nerve conduction velocity.
Methods.
All randomized controlled trials (RCTs) were found using PubMed, Cochrane, Springer, China National Knowledge Infrastructure (CNKI), and Wanfang Database of China Science Periodical Database (CSPD) by keyword search.
Meta-analysis was conducted using RevMan 5.0.
Results.
A total of 1552 participants were included in 24 trials.
Meta-analysis showed the incidence of all-grade neurotoxicity was significantly lower in experimental groups and high-grade neurotoxicity was also significantly less.
Effective percentage was significantly higher and sensory nerve conduction velocity was improved significantly, but changes in motor nerve conduction velocity were not statistically significant.
No adverse events associated with RA-based intervention were reported.
Conclusion.
RA-based intervention may be beneficial in relieving oxaliplatin-induced peripheral neuropathy.
However, more double-blind, multicenter, large-scale RCTs are needed to support this theory.
Trial Registration.
PROSPERO International prospective register of systematic reviews has registration number CRD42015019903.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Deng, Bo& Jia, Li-qun& Cheng, Zhiqiang. 2016. Radix Astragali-Based Chinese Herbal Medicine for Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1103983
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Deng, Bo…[et al.]. Radix Astragali-Based Chinese Herbal Medicine for Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1103983
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Deng, Bo& Jia, Li-qun& Cheng, Zhiqiang. Radix Astragali-Based Chinese Herbal Medicine for Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1103983
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1103983
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر