Investigation of the Key Pharmacological Activities of Ficus racemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD
المؤلفون المشاركون
Sumi, Salma Akter
Siraj, Md. Afjalus
Hossain, Amir
Mia, Md. Sagir
Afrin, Seagufta
Rahman, Md. Mustafizur
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Oxidative stress leads to numerous physiological disorders including infectious diseases, inflammation, and cancer.
The present study was carried out to investigate antioxidant, antibacterial, and cytotoxic activity of methanol crude extract of leaves and fruits of the Ficus racemosa (LCME and FCME, resp.) and to analyse its major bioactive polyphenols by HPLC-DAD.
Methods.
Antioxidant capacity of the extracts was evaluated by DPPH free radical scavenging, reducing power, total phenolic, total flavonoid, total tannin content assay, superoxide radical, hydroxyl radical, and hydrogen peroxide scavenging assay.
Identification and quantification of bioactive polyphenols were done by HPLC-DAD method.
Antibacterial activity was tested by “disc diffusion” method.
Brine shrimp lethality assay was carried out to check the cytotoxic potential.
Result.
Both LCME and FCME showed DPPH scavenging ability and concentration dependent reducing power activity.
They had phenolic content, flavonoid content, and tannin content.
Both the extracts showed superoxide radical scavenging ability, hydroxyl radical scavenging ability, and hydrogen peroxide scavenging ability.
HPLC analysis of LCME and FCME indicated the presence of significant amount of gallic acid along with other phenolic constituents.
Conclusion.
Significant amount of gallic acid along with other phenolic constituents might have played an important role in the observed antioxidant, antibacterial, and cytotoxic activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sumi, Salma Akter& Siraj, Md. Afjalus& Hossain, Amir& Mia, Md. Sagir& Afrin, Seagufta& Rahman, Md. Mustafizur. 2016. Investigation of the Key Pharmacological Activities of Ficus racemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104111
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sumi, Salma Akter…[et al.]. Investigation of the Key Pharmacological Activities of Ficus racemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1104111
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sumi, Salma Akter& Siraj, Md. Afjalus& Hossain, Amir& Mia, Md. Sagir& Afrin, Seagufta& Rahman, Md. Mustafizur. Investigation of the Key Pharmacological Activities of Ficus racemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104111
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104111
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر