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To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory
المؤلفون المشاركون
Ma, Zhi-guo
Liu, Hongjie
Li, Tianhao
Chen, Lingxiu
Zhan, Sha
Pan, Meilan
Li, Chenghua
Zhang, Zhe
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-29
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Aims.
To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs.
Methods.
The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data.
LR prediction model was established and the accuracy of the prediction by this model was evaluated.
Results.
The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties ( p < 0.05 ), and the coefficient was 0.178 ( p < 0.05 ); also they were related with five flavors ( p < 0.05 ), and the coefficient was 0.145 ( p < 0.05 ); they were not related with channel tropism ( p > 0.05 ).
There were totally 12 variables from four properties and five flavors for the LR.
Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204.
Conclusions.
Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity.
Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Hongjie& Li, Tianhao& Chen, Lingxiu& Zhan, Sha& Pan, Meilan& Ma, Zhi-guo…[et al.]. 2016. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104334
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Hongjie…[et al.]. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1104334
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Hongjie& Li, Tianhao& Chen, Lingxiu& Zhan, Sha& Pan, Meilan& Ma, Zhi-guo…[et al.]. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104334
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104334
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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