The Efficacy of Shen Shuaining Capsule on Chronic Kidney Disease: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Wang, Shanshan
Zhang, Jinfeng
Guo, Ming
Lian, Xiaobo
Sun, Miaomiao
Guo, Lizhong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-14
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the efficacy of Shen shuaining capsule on treating chronic kidney disease (CKD).
Methods.
All randomized controlled trials (RCTs) of Shen shuaining capsule in treating CKD were collected from CBM, CNKI, VIP, Wanfang, EMBASE, MEDLINE, PubMed, and Cochrane library clinical controlled trials database.
Two reviewers independently performed analysis of the included trials according to the inclusion and exclusion criteria.
The risk of bias tool was from the Cochrane Handbook version 5.1.0.
The Review Manager 5.2 software was employed for data analysis.
Funnel plot and Egger’s test were applied to evaluate publication bias.
Results.
20 studies including 1606 participants met the inclusion criteria, most of which were of low quality.
Meta-analysis indicated that Shen shuaining capsule was effective for CKD in terms of SCR, BUN, Hb, and response rate and with less adverse effects, of which SCR and BUN decreased significantly (MD = −84.72, 95% CI: −107.36, −62.07, P<0.00001) (MD = −4.30, 95% CI: −5.71, −2.89, P<0.00001); Hb and response rate increased significantly (MD = 9.94, 95% CI: 9.24, 10.64, P<0.00001) (OR = 4.25, 95% CI (3.32, 5.42), P<0.00001).
Conclusion.
Shen shuaining capsule significantly reduced SCR and BUN, increased HB, and improved total efficiency of the symptoms and signs in patients with CKD.
Subgroup analysis found that Shen shuaining capsule group was better than control group.
Due to low quality of the methodology of included studies, further high-quality researches were needed to study its efficacy and safety.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Shanshan& Zhang, Jinfeng& Guo, Ming& Lian, Xiaobo& Sun, Miaomiao& Guo, Lizhong. 2016. The Efficacy of Shen Shuaining Capsule on Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104358
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Shanshan…[et al.]. The Efficacy of Shen Shuaining Capsule on Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1104358
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Shanshan& Zhang, Jinfeng& Guo, Ming& Lian, Xiaobo& Sun, Miaomiao& Guo, Lizhong. The Efficacy of Shen Shuaining Capsule on Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104358
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104358
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر