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Effects of Hot Water Extracts from Polygonum multiflorum on Ovariectomy Induced Osteopenia in Mice
المؤلفون المشاركون
Kim, Jong-Jin
Kang, Kyung-Yun
Yee, Sung-Tae
Hwang, Yun-Ho
Lee, Sung-Ju
Paik, Soo-Heui
Son, Young-Jin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-26
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Polygonum multiflorum (PM), a traditional Chinese medicine, is used to treat various diseases including nonalcoholic fatty liver disease and hyperlipidemia.
However, the influence of PM on osteoporosis in animals is unclear.
The present study investigated the antiosteoporotic effect of PM on bone mass in ovariectomized (OVX) mice and its possible mechanism of action.
Twenty-five female C3H/HeN mice were divided into five groups of five mice as follows.
Sham-operated control mice received daily oral gavage of an equal volume of water, and OVX mice received daily oral gavage of water or an injection of β-estradiol or PM for 6 weeks.
Administration of PM significantly suppressed body weight and organs weight and increased weight and length of bone compared with the OVX group.
Treatment with PM reversed osteopenia in OVX mice, thereby improving the bone morphometric parameters.
Moreover, histological analysis using hematoxylin and eosin staining showed that PM inhibited OVX-induced bone loss.
Serum estradiol and bone alkaline phosphatase levels were significantly decreased in the OVX group, with the levels increasing with PM treatment.
In addition, tartrate-resistant acid phosphatase activity was inhibited by PM in OVX mice.
These results suggest that PM is effective in preventing bone loss in OVX mice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hwang, Yun-Ho& Kang, Kyung-Yun& Kim, Jong-Jin& Lee, Sung-Ju& Son, Young-Jin& Paik, Soo-Heui…[et al.]. 2016. Effects of Hot Water Extracts from Polygonum multiflorum on Ovariectomy Induced Osteopenia in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104460
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hwang, Yun-Ho…[et al.]. Effects of Hot Water Extracts from Polygonum multiflorum on Ovariectomy Induced Osteopenia in Mice. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1104460
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hwang, Yun-Ho& Kang, Kyung-Yun& Kim, Jong-Jin& Lee, Sung-Ju& Son, Young-Jin& Paik, Soo-Heui…[et al.]. Effects of Hot Water Extracts from Polygonum multiflorum on Ovariectomy Induced Osteopenia in Mice. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104460
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104460
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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