Aqueous Extract of Clerodendranthus spicatus Exerts Protective Effect on UV-Induced Photoaged Mice Skin
المؤلفون المشاركون
Zeng, Hui-Fang
Li, Yu-Cui
Xu, Lieqiang
Wang, Lan
Zhang, Xie
Li, Yong-xian
Li, Cai-lan
Zhang, Zhen-biao
Liang, Jia-li
Su, Zi-Ren
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-25
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Clerodendranthus spicatus (Thunb.) C.Y.Wu (CS) is commonly used to treat kidney diseases in traditional Chinese medicine for its prominent anti-inflammatory effect and nourishing function to kidneys.
In this study, aqueous extract of CS was assessed for its protective effect on UV-induced skin damage of mice.
The chemical compositions of CS aqueous extract were determined by HPLC-ESI-MS/MS, in which 10 components were identified.
During the experimental period, CS (0.9, 1.8, and 3.6 g/mL) was externally applied to shaved dorsal skins of mice prior to UV irradiation, daily for ten weeks.
The results presented that CS (3.6 g/mL) apparently improved photodamaged skin appearance such as erythema, edema, and coarseness.
The abnormal epidermal thickening was significantly reduced, and the dermal structures became more complete.
The underlying protective mechanisms were associated with improving antioxidant enzymes activities including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), downregulating inflammatory cytokines (IL-1β, IL-6, TNF-α, COX-2, and PGE2) expressions, recovering collagen density, and reducing matrix metalloproteinases productions.
Sun protection factor of CS (3.6 g/mL) was 16.21 ± 0.03 .
Our findings for the first time demonstrated that CS had therapeutic effect on the photoaged skin.
The results indicated that CS is a potential agent for photoprotective cosmetics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Lan& Zhang, Xie& Li, Yong-xian& Xu, Lieqiang& Li, Cai-lan& Zhang, Zhen-biao…[et al.]. 2016. Aqueous Extract of Clerodendranthus spicatus Exerts Protective Effect on UV-Induced Photoaged Mice Skin. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104520
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Lan…[et al.]. Aqueous Extract of Clerodendranthus spicatus Exerts Protective Effect on UV-Induced Photoaged Mice Skin. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1104520
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Lan& Zhang, Xie& Li, Yong-xian& Xu, Lieqiang& Li, Cai-lan& Zhang, Zhen-biao…[et al.]. Aqueous Extract of Clerodendranthus spicatus Exerts Protective Effect on UV-Induced Photoaged Mice Skin. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104520
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104520
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر