Phytochemical and Antinociceptive, Anti-Inflammatory, and Antioxidant Studies of Smilax larvata (Smilacaceae)
المؤلفون المشاركون
Cunha, Joice Maria
Hirota, Beatriz Cristina Konopatzki
Paula, Cristiane da Silva
Oliveira, Vinícius Bednarczuk de
Schreiber, Anne Karoline
Ocampos, Fernanda Maria Marins
Barison, Anderson
Miguel, Obdulio Gomes
Miguel, Marilis Dallarmi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-22
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The tea of aerial parts of Smilax larvata Griseb.
(Smilacaceae) has been ethnopharmacologically used in Southern Brazil due to its anti-inflammatory action.
In this study, ethanolic and organic extracts from aerial parts of S.
larvata were phytochemically and pharmacologically characterized.
The phytochemical analysis of EtOAc extract of S.
larvata revealed the presence of three flavonoids, drabanemoroside, kaempferol 3-O-α-L-rhamnopyranosyl(1→2)-α-L-rhamnopyranoside, and kaempferol, the first two being isolated for the first time in this genus, two phenolic compounds p-hydroxybenzoic acid and p-coumaric acid, and alkaloids.
In vitro assays demonstrated a potential antioxidant property of SLG.
The treatment with SLG induced a significant reduction of the formalin-evoked flinches in rats, an effect reversed by opioid antagonist naloxone.
Treatment with SLG also induced a significant increase in the hot plate latency and a decrease of intestinal motility by 45%.
No effect was observed over nociceptive responses induced by a TRPA1 agonist mustard oil or over acetic acid-induced writhing in mice.
Together, our data suggested that SLG has an in vivo antinociceptive effect, which seems to be associated with the opioid system activation.
These findings support previous claims of medical use of Smilax larvata in the treatment of pain conditions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hirota, Beatriz Cristina Konopatzki& Paula, Cristiane da Silva& Oliveira, Vinícius Bednarczuk de& Cunha, Joice Maria& Schreiber, Anne Karoline& Ocampos, Fernanda Maria Marins…[et al.]. 2016. Phytochemical and Antinociceptive, Anti-Inflammatory, and Antioxidant Studies of Smilax larvata (Smilacaceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1104541
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hirota, Beatriz Cristina Konopatzki…[et al.]. Phytochemical and Antinociceptive, Anti-Inflammatory, and Antioxidant Studies of Smilax larvata (Smilacaceae). Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1104541
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hirota, Beatriz Cristina Konopatzki& Paula, Cristiane da Silva& Oliveira, Vinícius Bednarczuk de& Cunha, Joice Maria& Schreiber, Anne Karoline& Ocampos, Fernanda Maria Marins…[et al.]. Phytochemical and Antinociceptive, Anti-Inflammatory, and Antioxidant Studies of Smilax larvata (Smilacaceae). Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1104541
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104541
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر