Using Fresh Frozen Plasma for Acute Airway Angioedema to Prevent Intubation in the Emergency Department: A Retrospective Cohort Study
المؤلفون المشاركون
Saeb, Aya
Hagglund, Karen H.
Cigolle, Christine T.
المصدر
Emergency Medicine International
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Angioedema (AE) is a common condition which can be complicated by laryngeal edema, having up to 40% mortality.
Although sporadic case reports attest to the benefits of fresh frozen plasma (FFP) in treating severe acute bouts of AE, little evidence-based support for this practice is available at present.
Study Objectives.
To compare the frequency, duration of intubation, and length of intensive care unit (ICU) stay in patients with acute airway AE, with and without the use of FFP.
Methods.
A retrospective cohort study was conducted, investigating adults admitted to large community hospital ICU with a diagnosis of AE during the years of 2007–2012.
Altogether, 128 charts were reviewed for demographics, comorbidities, hospital courses, and outcomes.
A total of 20 patients received FFP (108 did not).
Results.
Demographics and comorbidities did not differ by treatment group.
However, nontreated controls did worse in terms of intubation frequency (60% versus 35%; p = 0.05 ) and ICU stay (3.5 days versus 1.5 days; p < 0.001 ).
Group outcomes were otherwise similar.
Conclusion.
In an emergency department setting, the use of FFP should be considered in managing acute airway nonhereditary AE (refractory to steroid, antihistamine, and epinephrine).
Larger prospective, better controlled studies are needed to devise appropriate treatment guidelines.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Saeb, Aya& Hagglund, Karen H.& Cigolle, Christine T.. 2016. Using Fresh Frozen Plasma for Acute Airway Angioedema to Prevent Intubation in the Emergency Department: A Retrospective Cohort Study. Emergency Medicine International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104572
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Saeb, Aya…[et al.]. Using Fresh Frozen Plasma for Acute Airway Angioedema to Prevent Intubation in the Emergency Department: A Retrospective Cohort Study. Emergency Medicine International No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1104572
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Saeb, Aya& Hagglund, Karen H.& Cigolle, Christine T.. Using Fresh Frozen Plasma for Acute Airway Angioedema to Prevent Intubation in the Emergency Department: A Retrospective Cohort Study. Emergency Medicine International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104572
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104572
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر