Comparison of the Effects of Glutamine, Curcumin, and Nesfatin-1 on the Gastric Serosal Surface Neomucosa Formation: An Experimental Rodent Model
المؤلفون المشاركون
Gulcicek, Osman Bilgin
Solmaz, Ali
Yiğitbaş, Hakan
Ercetin, Candas
Yavuz, Erkan
Ozdogan, Kamil
Arici, Sinan
Akkalp, Asli Kahraman
Sarac, Tulin
Çelebi, Fatih
Celik, Atilla
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Short bowel syndrome can crop up if more than 50% of small intestine is resected or when less than 100 cm of small bowel is left.
Glutamine is the main food source of enterocytes.
Curcumin has protective effects on intestinal ischemia-reperfusion damage.
Nesfatin-1 is a satiety molecule.
It has protective effects on gastric mucosa.
The primary purpose of this study is to compare effects of glutamine, curcumin, and nesfatin-1 on the gastric serosal surface neomucosa formation on rats.
Materials and Methods.
24 Wistar-Hannover rats were randomly divided into 4 groups and treated with saline, glutamine, curcumin, and nesfatin-1 after ileogastric anastomosis.
After 14 days all rats were euthanized, and blood was collected.
En bloc resection of anastomotic part was performed for histopathological examination.
Results.
PDGF, TGF-β, and VEGF levels and neomucosa formation were higher in glutamine group ( p = 0.003 , p = 0.003 , and p = 0.025 ).
Glutamine promotes the intestinal neomucosa formation on the gastric serosal surface and augments growth factors essential for neomucosa formation on rats.
Conclusion.
Glutamine may be used in short bowel syndrome for increasing the absorption surface area.
But that needs to be determined by adequately powered clinical trials.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gulcicek, Osman Bilgin& Solmaz, Ali& Yiğitbaş, Hakan& Ercetin, Candas& Yavuz, Erkan& Ozdogan, Kamil…[et al.]. 2016. Comparison of the Effects of Glutamine, Curcumin, and Nesfatin-1 on the Gastric Serosal Surface Neomucosa Formation: An Experimental Rodent Model. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104609
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gulcicek, Osman Bilgin…[et al.]. Comparison of the Effects of Glutamine, Curcumin, and Nesfatin-1 on the Gastric Serosal Surface Neomucosa Formation: An Experimental Rodent Model. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104609
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gulcicek, Osman Bilgin& Solmaz, Ali& Yiğitbaş, Hakan& Ercetin, Candas& Yavuz, Erkan& Ozdogan, Kamil…[et al.]. Comparison of the Effects of Glutamine, Curcumin, and Nesfatin-1 on the Gastric Serosal Surface Neomucosa Formation: An Experimental Rodent Model. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104609
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104609
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر