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Cytokines as Early Markers of Colorectal Anastomotic Leakage: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Kleinrensink, Gert-Jan
Sparreboom, Cloë L.
Wu, Zhouqiao
Dereci, Adem
Boersema, Geesien S. A.
Menon, Anand G.
Ji, Jiafu
Lange, Johan F.
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-09
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Purpose.
Colorectal anastomotic leakage (CAL) is one of the most severe complications after colorectal surgery.
This meta-analysis evaluates whether systemic or peritoneal inflammatory cytokines may contribute to early detection of CAL.
Methods.
Systematic literature search was performed in the acknowledged medical databases according to the PRISMA guidelines to identify studies evaluating systemic and peritoneal levels of TNF, IL-1β, IL-6, and IL-10 for early detection of CAL.
Means and standard deviations of systemic and peritoneal cytokine levels were extracted, respectively, for patients with and without CAL.
The meta-analysis of the mean differences was carried out for each postoperative day using Review Manager.
Results.
Seven articles were included.
The meta-analysis was performed with 5 articles evaluating peritoneal cytokine levels.
Peritoneal levels of IL-6 were significantly higher in patients with CAL compared to patients without CAL on postoperative days 1, 2, and 3 (P<0.05).
Similar results were found for peritoneal levels of TNF but on postoperative days 3, 4, and 5 (P<0.05).
The articles regarding systemic cytokine levels did not report any significant difference accordingly.
Conclusion.
Increased postoperative levels of peritoneal IL-6 and TNF are significantly associated with CAL and may contribute to its early detection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sparreboom, Cloë L.& Wu, Zhouqiao& Dereci, Adem& Boersema, Geesien S. A.& Menon, Anand G.& Ji, Jiafu…[et al.]. 2016. Cytokines as Early Markers of Colorectal Anastomotic Leakage: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104670
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sparreboom, Cloë L.…[et al.]. Cytokines as Early Markers of Colorectal Anastomotic Leakage: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1104670
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sparreboom, Cloë L.& Wu, Zhouqiao& Dereci, Adem& Boersema, Geesien S. A.& Menon, Anand G.& Ji, Jiafu…[et al.]. Cytokines as Early Markers of Colorectal Anastomotic Leakage: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104670
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104670
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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